[8] NEGRAO M V,LAM V K,REUBEN A,et al. PD-L1 Expression,tumor mutational burden,and cancer gene mutations are stronger predictors of benefit from immune checkpoint blockade than HLA class Ⅰ genotype in non-small cell lung...
HLA expression in a primary uveal melanoma, its cell line, and four of its metastases. Br J Ophthalmol 1997;81:989-93.Blom DJ, Schurmans LR, Waard-Siebinga I, Wolff-Rouendaal D, Keunen JE, Jager MJ (1997b) HLA expression in a primary uveal melanoma, its cell line, and four of ...
•平均 mHLA-DR 表达:19976 AB/C•标准偏差:1846 AB/C•变异系数:9.2% 参考文献:Gossez M, Bonnet B, Boussaid I, et al. Multicenter inter-laboratory quality control of monocyte HLA-DR expression by flow cytometry. Cytometry B C...
[8] NEGRAO M V,LAM V K,REUBEN A,et al. PD-L1 Expression,tumor mutational burden,and cancer gene mutations are stronger predictors of benefit from immune checkpoint blockade than HLA class Ⅰ genotype in non-small cell lung cancer[J]. J Thorac Oncol,2019,14(6):1021-1031. DOI:10. 1016...
PMID: 34245634.[8] NEGRAO M V,LAM V K,REUBEN A,et al. PD-L1 Expression,tumor mutational burden,and cancer gene mutations are stronger predictors of benefit from immune checkpoint blockade than HLA class Ⅰ genotype in non-small cell lung cancer[J]. J Thorac Oncol,2019,14(6):1021-1031...
Source: Prokaryotic expressionHost: E.coliResidues: Gly30~Ser266Tags: N-terminal His TagSubcellular Location: MembranePurity: > 95%Traits: Freeze-dried powderBuffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% skl, 5%Trehalose....
L:Low cell surface expression 在细胞表面低表达 S:Soluble 该等位基因表达的蛋白可溶 C:Cytoplasm 表达的蛋白在细胞质 A:Aberrant 不确定是否表达 Q:Questionable 可疑的,该等位基因中的变异会影响其他等位基因的正常表达 HLA分型的解析度: 可以分为 1.低解析度(low resolution):至精确到第一个数字区域,例如:A...
HLA 全称human leukocyte antigen, 表示人类白细胞抗原,是编码主要组织相容性复合体(MHC)的基因,位于6p21.31的区域,包含了一系列紧密连锁的基因座。与人类的免疫系统功能密切相关。 HLA全长约3.6M, 含有220多种功能不同的基因,是目前已知的人类染色体中基因密度最高,多态性最为丰富的区域,位置示意图如下 ...
ESTIMATE (Estimation of STromal and Immune cells in MAlignant Tumor tissues using Expression data) is a tool for predicting tumor purity, and the presence of infiltrating stromal/immune cells in tumor tissues using gene expression data. ESTIMATE algorithm is based on single sample Gene Set Enrichment...
However, MSC differentiated to osteoblasts, chondrocytes, and adipocytes lack class II alloantigen expression even after IFN-γ stimulation, but still possess a profound inhibitory effect on lymphocyte alloreactivity. Thus, the immunomodulatory effect by MSC appears to be alloantigen independent, ...