The invention discloses a cell strain with specific expression of HLA-G1 antigen. The preservation number is CCTCC: C201351. The preservation date is on May 8, 2013. The preservation place is China Center for Type Culture Collection. The molecular weight of the HLA-G1 antigen produced by ...
K562/AO2细胞表面HLAI类分子和MICA/B的表达 NK细胞杀伤活性 参考文献 1栾风君,杨纯正,马建国等.一株红白血病多药耐药细 胞系(K562/AO2)的建立及其耐药特性的研究.中华肿瘤杂志, 1993 正文 作者:**转牛新清郭坤元周健魏红梅 摘要:本研究探讨K562亲本细胞株及多药耐药细胞株 K562/AO2细胞表面HLAI类分子和MHCI类...
目的:与经典HLA I类分子相比,HLA-G分子的组织分布有限.甲基化导致的基因沉默现象是表观遗传学领域研究的热点之一,本文研究K562细胞系HLA-G基因启动子区甲基化状态及其与基因表达的关系.方法:应用亚硫酸氢钠脱氨基-DNA测序(bisulphite sequencing)的方法检测经5-氮胞苷(5-aza-2'-deoxy- cytidine)处理前后的K562细胞...
靶细胞表达HLAG1分子可明显抑制NK细胞的杀伤效应: :关键词:HLAG1;NK细胞;转染 [中图分类号] R39212 [文献标识码] A ExpressionofHLA--G1antigenonK562cellinhibitscytotoxicityme-- diatedbyNKfromPBMC HANJunyan.HUANGYa—fei,WUXiongwen,GONGFei—li ...
Expression of HLA C lass I M olecules and MHC C lass I Chain re lated M olecules A /B in K 562and K 562/AO 2Cell L ines and Their E ffects on Cytotoxicity ofNK C ells M EI Jia Z huan,N I U X in Q ing,GUO Kun Y uan,ZHOU Jian,WE I H ong M ei D epart...
I. CsA allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR. J Immunol 1980... AD Hess,PJ Tutschka,GW Santos - 《Journal of Immunology》 被引量: 692发表: 1981年...
The KIR3DL1 gene is a member of killer immunoglobulin-like receptors family, which exhibits a variegated expression pattern in NK cells and subsets of CD4+... None - 《Lancet》 被引量: 0发表: 2008年 Mind the gap: lack of association between KIR3DL1*004/HLA-Bw4-induced natural killer ...
.TheproliferationreactionoflymphocytecellswasdetectedbyMTTcolorimetry.ResultsAfter96htreatmentwithA23187(375ug/ml)andPMA(10μg/mL),thecellsexhibitedthecharacteristicDCmorphology,CD83,CD86,CD80,CD40andHLA DR,CD1aexpressionwasupregulatedandthecellswerefoundtobeabletostronglystimulatetheproliferationofallogeneicTcells...
文章编号(ArticleID):1009-2137(2011)05-1112-05·论著· 稳定表达HLA-A * 1101蛋白的K562细胞株的建立 査显丰 1 ,周羽竝 2 ,杨力建 1 ,陈少华 1 ,李萡 1 ,闫小娟 1 ,李扬秋 1,3 暨南大学医学院 1 血液病研究所; 2 生化教研室; 3 再生医学教育部重点实验室,广东广州510632 摘要本研究目的是建立...
HLA—E与NK受体之间的相互作用和HLA—E体外表达对NK细胞功能的影响奠定了基础。 关键词 HLA—E;真核表达载体;K562细胞;先导肽 中图分类号 R733.7;Q782 文献标识码 A Construction0fpcDNA3.1(+)/A2EEukaryoticExpressionVectorand ItsExpression0nK562cell ...