HIV蛋白酶抑制剂是一种抗病毒药物,现用于AIDS的治疗。 虽然对艾滋病的治疗有作用,但其会产生副作用。 基本信息 中文名称 HIV蛋白酶抑制剂 外文名称 HIV protease inhibitors 化学式 C22H33N3O4 分子量 403.51512 CAS登录号 160369-84-6 目录 1InChI编码 ...
Merck’s indinavir (Crixivan) was the third protease inhibitor on the market. Merck began their research on HIV protease inhibitors in 1986 with Irving Sigal, a senior director in the Department of Molecular Biology, as the project champion. They initially also screened their renin inhibitors for ...
Although protease acts at the last step of the virus life cycle, protease inhibitors were discovered shortly after nucleoside reverse transcriptase inhibitors. The era of HIV protease inhibitor drugs began in 1996 with the i...
NNRTIs:Non-Nucleoside Reverse Transcriptase Inhibitors,即非核苷逆转录酶抑制剂,也是一类抗HIV药物,通过干扰逆转录酶活性来抑制病毒。 PIs:Protease Inhibitors,即蛋白酶抑制剂,这些药物通过阻止病毒蛋白酶的活性来抑制HIV-1。 INSTIs:Integrase Strand Transfer Inhibitors,即整合酶链转移抑制剂,是一类抗HIV药物,通过抑...
PIs:Protease Inhibitors,即蛋白酶抑制剂,这些药物通过阻止病毒蛋白酶的活性来抑制HIV-1。 INSTIs:Integrase Strand Transfer Inhibitors,即整合酶链转移抑制剂,是一类抗HIV药物,通过抑制整合酶来阻止病毒整合到宿主DNA中。 INBIs:Integrase Binding Inhibitors,即整合酶结合抑制剂,这些药物通过不同的机制抑制整合酶活性。
网络抑制剂 网络释义 1. 抑制剂 抑制剂(HIV protease inhibitors),或nefazodone,尤其与较高剂量的simvastatin并用时(参见下文;药品交互作用中,与CY… mab.mnd.gov.tw|基于2个网页 例句 释义: 全部,抑制剂
Just a few years after the sequence of the HIV genome became available, inhibitors of such a protein, the HIV protease, were close to being used in the experimental AIDS therapy. Several factors contributed to this rapid progress. Sequence homologies of HIV-1, with previously studied ...
PIs:Protease Inhibitors,即蛋白酶抑制剂,这些药物通过阻止病毒蛋白酶的活性来抑制HIV-1。 INSTIs:Integrase Strand Transfer Inhibitors,即整合酶链转移抑制剂,是一类抗HIV药物,通过抑制整合酶来阻止病毒整合到宿主DNA中。 INBIs:Integrase Binding Inhibitors,即整合酶结合抑制剂,这些药物通过不同的机制抑制整合酶活性。
目前,临床常用的ART药物中,非核苷逆转录酶抑制剂(non-nucleoside reverse transcriptase inhibitors,NNRTIs)、蛋白酶抑制剂(protease inhibitors,PIs)、INSTIs均会导致不同程度的体重增加。但是,与NNRTIs、PIs相比,INSTIs对HIV感染者体重增加的影响更显著。美国...
5) protease inhibitors 蛋白酶抑制药6) protease inhibitor 蛋白酶抑制药补充资料:结晶胰蛋白酶 ,胰蛋白酶 药物名称:结晶胰蛋白酶英文名:Trypsin别名: 结晶胰蛋白酶 ,胰蛋白酶外文名:Trypsin 适应症: 1.用于脓胸、血胸、外科炎症、溃疡、创伤性损伤、娄管等所产生的局部水肿、血肿、脓肿。 2.用于呼吸道疾病...