1,2 In the last two decades, the Hippo signaling pathway has been established as a central regulator of organ size. The Hippo pathway was first identified by genetic mosaic screens for tumor suppressors or growth-related genes in Drosophila. For instance, deletion of Warts (wts) leads to ...
Using real-time PCR, research studies can easily and reliably analyze components of the Hippo signaling pathway with this array. ProductSpeciesTechnologyCat. No.Drug Metabolism PCR ArrayHumanGene ExpressionPAHS-002ZDrug Metabolism PCR ArrayMouseGene ExpressionPAMM-002ZDrug Metabolism PCR ArrayRatGene ...
This is the first report characterizing the expression and protein localization of Hippo pathway components during bovine oocyte maturation. Results provide new knowledge that the Hippo signaling pathway is involved during oocyte maturation in bovine species, and that the expression and localization of ...
Hippo信号通路PCR芯片 Hippo Signaling PCR Array 联系购买 配送服务: 运费￥0.00 数量: (库存9999件) 产品详细 地区:上海 简介:Hippo Signaling PCR Array 提供商:SAB 服务名称:Hippo Signaling PCR Array Human Hippo Signaling PCR Array The Human Hippo Signaling Pathway RT² Profiler PCR Array profiles the...
Control of cell number and organ size is critical for appropriate development and tissue homeostasis. Studies in both Drosophila and mammals have established the Hippo signaling pathway as an important modulator of organ size and tumorigenesis. Upon acti
The interaction between the Hippo pathway and the EGFR signaling pathway in lung adenocarcinoma (LUAD) is intricate. Previous research has demonstrated that inhibiting the Hippo pathway can activate the EGFR signaling pathway, resulting in resistance to EGFR-TKIs. For example, Vichas et al. found ...
EndoMT has been implicated in driving the pathogenesis of fibrosis in multiple fibrotic conditions, including SSc34. The Hippo pathway is a highly conserved signaling pathway that regulates cell proliferation, apoptosis, and stemness in response to a wide range of extracellular and intracellular ...
The Hippo pathway is crucial in organ size control and tumorigenesis. Dysregulation of the Hippo/YAP axis is commonly observed in gastric cancer, while effective therapeutic targets for the Hippo/YAP axis are lacking. Identification of reliable drug targ
报告题目:Hippo signaling in innate anti-microbial immunity The Hippo pathway has been established as a key regulator of tissue homeostasis and organ size control in multiple organisms. Recently, patients bearing a loss-of-function mutation of Mst1, the mammalian ortholog of Drosophila Hippo, are re...
Hippo pathway therapeutics and new avenues to modulate pathway activity are beginning to emerge. Abstract The Hippo pathway controls organ size in diverse species, whereas pathway deregulation can induce tumours in model organisms and occurs in a broad range of human carcinomas, including lung, colore...