High-throughput sequencingFunctional geneMicrobial diversityOver the past years, the traditional cultivation-independent genomic approaches which rely on the preexisting knowledge about gene sequence, have significantly promoted our understanding of the structural and functional diversity of bioleaching ...
High throughput sequencing DNA databases are available for severaldecapodspecies to underlie genomic andtranscriptomicresponses to environmental, pathological and physiological stressors (Table 1). Although at the onset of this review, studies on the investigation of digestive system are scarce (Wang...
Ward RM et al (2013) Big data challenges and opportunities in high-throughput sequencing. Syst Biomed 1(1):29-34WARD R M; SCHMIEDER R; HIGHNAM G;.Big data challenges and opportunities in highthrough-put sequencing.Systems Biomedicine.2013.29-34...
In this article, we review the recent advances in immune repertoire study of infectious diseases, which were achieved by traditional techniques and high-throughput sequencing (HTS) techniques. HTS techniques enable the determination of complementary regions of lymphocyte receptors with unprecedented ...
We also assess the impact of genotyping, genome sequencing and personal omics profiling on medical applications, including diagnosis and disease monitoring. Finally, we review recent developments in single???cell sequencing, and conclude with a discussion of possible future advances and obstacles for ...
In this concise review we provide selected examples of how high throughput sequencing is being applied to understand the biology of bacterial pathogens, and discuss future technological advances likely to have a profound impact on the field. 展开 ...
High-throughput sequencing (HTS) studies of fungal communities are redrawing the map of the fungal kingdom by hinting at its enormous - and largely uncharted - taxonomic and functional diversity. However, HTS approaches come with a range of pitfalls and potential biases, cautioning against unwary ...
Recent papers have described the first application of high-throughput sequencing (HTS) technologies to the characterization of transcriptomes. These studies emphasize the tremendous power of this new technology, in terms of both profiling coverage and quantitative accuracy. Initial discoveries include the ...
(CGr) leaves using high-throughput sequencing method. The potential miRNA target genes were predicted and annotated using the NR, Swiss-Prot, GO, COG, KEGG, KOG and Pfam databases. The main biological processes regulated by miRNAs were revealed. The miRNAs which potentially play important roles ...
The DNA sequencing technology is one of the most powerful tools in modern life science research,and the high-throughput sequencing technologies play a key role in genomic sequencing of different organisms.Here,we presented a brief review of the invention and development of the DNA sequencing technolo...