Review discharge medication prescriptions for continuation of high intensity statin and compare admission statin to the discharge statin prescriptionThe findings of this review will be used to assist in modifying protocols that promote appropriate statin dosing for secondary prevention in high-risk coronary...
The 2013 American College of Cardiology/American Heart Association guidelines on cholesterol management have placed greater emphasis on high-intensity statin dosing for those with known cardiovascular disease or diabetes mellitus. Differences in risk of hepatotoxicity, new onset DM and rhabdomyolysis ...
et al. CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin. Eur J Med Res 29, 539 (2024). https://doi.org/10.1186/s40001-024-02109-7 Download citation Received10 June 2024 Accepted14 October 2024 Published...
For monthly dosing, PCSK9 levels were reduced more in the moderate-intensity statin groups (up to 33%) than in the high-intensity statin groups (up to 16%) (eTable 5 in Supplement). Tolerability and Safety Adverse events occurred in 36% of evolocumab-treated patients, 40% of ezetimibe-...
The ASTEROID trial even showed regression of coronary atherosclerosis with very high-intensity statin therapy (Nissen et al., 2006). Similarly, Yu et al. showed that intensive but not regular-dose atorvastatin therapy resulted in regression of carotid atherosclerotic disease (Yu et al., 2007) and...
DOSING & MOA COVERAGE & RESOURCES Connect With a Rep Your patients with established CVD are at risk for a CV event Don’t wait for tomorrow.Act now. Add Repatha®to dramatically lower LDL-C and reduce the risk of MI, stroke, or coronary revascularization.1 ...
For statin-treated patients, the intensity of statin therapy was categorized as low intensity (simvastatin 10 mg, pravastatin 10–20 mg, or fluvastatin 20–40 mg), moderate intensity (atorvastatin 10–20 mg, rosuvastatin 5–10 mg, simvastatin 20–80 mg, pravastatin 40 mg, or fluvastatin 80 ...
High-intensity statin therapy (atorvastatin 40–80 mg/day or rosuvastatin 20–40 mg/day) generally reduces LDL-C levels by ≥50% while moderate-intensity statin therapy reduces LDL-by ≥30% to <50%. However, high-intensity statin therapy may be insufficient to achieve LDL-C targets when ...
High-intensity statin therapy (atorvastatin 40–80 mg/day or rosuvastatin 20–40 mg/day) generally reduces LDL-C levels by ≥50% while moderate-intensity statin therapy reduces LDL-by ≥30% to <50%. However, high-intensity statin therapy may be insufficient to achieve LDL-C targets when ...
The concentration of ROS in the sample was quantified by its ability to inhibit the binding of the anti-ROS antibody to the immobilized ROS-BSA and subsequently the color intensity in the assay wells. The assay enabled the determination of ROS in plasma at concentrations as low as 40 pg/ml...