Intensive-dose therapy was not associated with lower all-cause mortality compared with moderate-dose statin therapy (OR, 0.93; 95% CI, 0.81-1.05; 1318 cases/16 408 patients receiving intensive therapy vs 1360 cases/16 342 patients receiving moderate doses). Intensive statin therapy was not ...
additionally, published data from a fourth large clinical trial suggested the possibility of a deterioration in glucose control in patients receiving intensive statin therapy, and a recent report of 220 patients with hypercholesterolemia treated with placebo or different doses of atorvastatin and followed...
LAPLACE-2 is to our knowledge the first study to demonstrate that the addition of evolocumab results in similar percent reductions in LDL-C and achieved LDL-C levels regardless of stable baseline statin type, dose, or intensity, across 3 commonly prescribed statins and a broad range of doses....
because it could be easily implemented in a comprehensive MDCT protocol without increase of patient risks, it is possible that CTDE could be optimized using different parameters—namely higher tube current and current intensity or dedicated injections of higher doses of contrast—as the ideal CTDE ...
Grines, MD; Anthony N. DeMaria, MD; for the REVERSAL Investigators Author Affiliations JAMA. 2004;291(9):1071-1080. doi:10.1001/jama.291.9.1071 editorial comment icon Editorial Comment multimedia icon Multimedia Editorial High-Intensity Statin Treatment for Coronary Heart Disease Frank M. Sacks,...