Plasma LDL-C goal of <100 mg/dl and <70 mg/dl was achieved in 84.3% and 38.0% respectively, with no significant difference between the low- and moderate-intensity statin users. LDL-C reductions ≥50% can b
Limitations Data on whether participants were taking a maximally-tolerated statin dosage were unavailable. Conclusions The 2018 AHA/ACC cholesterol guideline identifies adults with CKD who have very high atherosclerotic CVD risk despite taking a moderate/high-intensity statin....
Fluvastatin XL was associated with the lowest rate of muscular symptoms (5.1%) among individual statins.Conclusion : PRIMO demonstrated that mild to moderate muscular symptoms with high-dosage statin therapy may be more common and exert a greater impact on everyday lives than previous...
Bruckert, E., Hayem, G., Dejager, S., Yau, C., & Begaud, B. (2005). Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients--the PRIMO study. Cardiovascular Drugs and Therapy, 19(6), 403-414....