We reviewed the role of transcription factors HIF-1α and its signaling pathway in the occurrence of disease , and introduced to the relationship among HIF-1α and growth, development, inflammation and tumor , then carryed out the prospect, in order to better be used in biomedical. Key ...
【关键词】 间充质干细胞动员;DMOG;缺氧诱导因子一1;基质细胞衍生因子一let;血管内皮生长因子 【中图分类号】R332 【文献标识码】A 【文章编号】1671.7856(2015)01-0009-06 doi:10.3969.j.issn.1671.7856.2015.O01.002 MechanismofHIF一1signalingpathwayinmediating MSCsmobilizationwithDMoG HUShao-jun’,YUQin’,...
HIF-1α可以与上下游多种蛋白组成不同的信号通路,介导低氧信号,调控细胞产生一系列对缺氧的代偿反应, 在机体的生长发育及生理和病理过程中发挥重要作用,是生物医学研究的一个焦点。对转录因子HIF-1α及其信号通路在疾病发生 中的作用进行了综述,介绍了HIF-1α在动物生长发育、炎症和肿瘤中的研究概况,并进行了展望,...
应激的 HIF-1 信号通路王苹苹,孔繁平,陈学群,杜继曾( 浙江大学医学院 基础医学系,浙江 杭州 310058)综述[摘要]低氧诱导因子( hypoxia inducible factor, HIF) 由 HIF- 1α 和 HIF- 1β 两个亚基组成, 在低氧下其能激活多种靶基因的转录,在细胞、组织生长发育和生理应激, 以及某些病理过程中具有重要的作用...
Learn here about the HIF-1 signaling pathway and its impact on oxygen homeostasis and cellular adaptation. Click here.
任明. 低剂量参麦方调控HIF-1/VEGF信号通路对心力衰竭大鼠的改善作用. 天津中医药大学学报, 2024, 43(10): 900-906.WANG Zhe, GUO Liuli, LIU Yiman, ZHUANG Pengwei, REN Ming. The improvement effect of low-dose Shenmai...
10. Lv C, Li Z, Wang Q, Wang Y, Zhao X, Zhang Y. miRNA-150_R-1 mediates the HIF-1/ErbB signaling pathway to regulate the adhesion of endometrial epithelial cells in cows experiencing retained placenta. Front Vet Sci 2022, 9: 1037880. ...
www.nature.com/scientificreports OPEN received: 27 January 2016 accepted: 18 May 2016 Published: 06 June 2016 Docetaxel induced-JNK2/PHD1 signaling pathway increases degradation of HIF-1α and causes cancer cell death under hypoxia Eun-Taex Oh1,2, Chan Woo Kim3, Soo Jung Kim1,...
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