Melatonin Inhibits the Metastatic Ability of HER2/neu-negative Breast Cancer Cells by Suppressing Epithelial-to-Mesenchymal Transition (EMT)-Associated Genes with Predictive and Prognostic Relevancedoi:10.1093/annonc/mdx513.009A. TavartkiladzeG. Simonia...
her2/neu有关癌基因的例句:1.If the cancer tests negative for over-expression of the her2/ neu oncogene, weekly chemotherapy with taxol or taxotere is an effective option with acceptable side effects. 如果发现癌基因her2/neu表达降低，那么每周一次的化疗和紫杉烷类或泰索帝一起使用疗效显著，...
· negative regulation of immature T cell proliferation in thymus · wound healing · myelination · positive regulation of MAP kinase activity · innate immune response · positive regulation of translation · regulation of angiogenesis · positive regulation of cell adhesion · positive regulation of ...
Trastuzumab has become a critical component of the treatment of patients with HER2-neu positive tumors, but the effect of treatment in patients with small tumors and node-negative disease has not been evaluated in clinical trials. Current guidelines have category 3 recommendations to consider the ...
her2/neu是什么意思her2/neu是什么意思Ifthecancertestsnegativeforover-expressionoftheher2/neuoncogene,...
摘要: HER2 is a 185 kDa transmembrane glycoprotein in the receptor tyrosine kinase family that also includes EGFR or HER1 (erbB1), HER3 (erbB3), and HER4 19 (erbB4). HER2 gene amplification and protein...关键词: erbB2/neu. See Human epidermal growth factor receptor 2 (HER2 Human ...
before operation,the expression of GCDFP-15,ER,PR,C-erbB-2,HER2/Neu in breast cancer tissue samples were detected by immunohistoc-hemistry.Results The negative rate of GCDFP-15,ER,PR,C-erbB-2and HER2/Neu were 61.00%,50.00%,36.00%,62.00%and 45.00%,respectively.The negative rate ...
The study assessed whether the composition, concentrations, and exposure duration of BPA, EE, NPH, and DDT significantly altered copy numbers in estrogen and receptor positive or negative breast cancer lines. Each line was randomly assigned to cases (exposed) and control (unexposed) groups using ...
et al. HER2/NEU gene amplification characterized by fluorescence in situ hybridization: poor prognosis in node-negative breast carcinomas. J. Clin. Oncol. 15, 2894-2904 The HER-2/neu gene codes for a membrane receptor protein that is homologous, but distinct from the epidermal growth factor ...
Expression of HER2/neu has also been reported to be a negative prognostic factor in a small survey of NT tumors. Here, we have investigated HER2/neu expression in 14 human and 2 murine neuroblastoma (NB) cell lines by flow cytometric analysis and in 93 NT by means of a certified ...