Insights into the immunopathogenesis of chronic HBV infections are fundamental in the quest for novel treatment approaches aimed at a functional cure. While much is known about the ineffective HBV-specific T-cell responses that characterise persistent HBV replication, B cells have been left largely und...
Natural products (NPs), sourced from plants, animals, fungi, and microorganisms and their analogs [5], emerge as promising candidates in the quest for effective anti-HBV agents due to their diverse structures, broad bioactivity, and minimal toxicity. While these compounds can be classified into ...
VDJ gene segments were identified and aligned using IMGT/HighV-QUEST41. VDJ sequences were extracted to construct a personal immunoglobulin amino acid sequence library for MS/MS data- base search. Protein identification and quantification were performed using MaxQuant9. The intensities of iTRAQ ...
The virus of hepatitis B was identified and described well before the hepatitis A virus was identified; the quest for the former and the development of increasingly sensitive immunologic techniques helped immeasurably to facilitate the discovery of the latter. There are several reasons for hepatitis; ...
Hepatitis C virus infection and related liver disease: the quest for the best animal model. Front Microbiol. 2013;4:213. [PubMed] [DOI] [Cited in This Article: 1] [Cited by in Crossref: 29] [Cited by in F6Publishing: 31] [Article Influence: 2.6] [Reference Citation Analysis (0)...
Kretchmar,R Scott - 《Quest》 被引量: 15发表: 2005年 The ethical limits of bungee research in ICTD engagement is unethical, and we suggest some minimal conditions that are necessary, but not sufficient, for such visits to be ethically defensible in ICTD... A Dearden,WD Tucker - IEEE 被...
Comparative analysis of human and mouse immunoglobulin variable heavy regions from IMGT/LIGM-DB with IMGT/HighV-QUEST. Theor Biol Med Model 11, 30 (2014). Article Google Scholar Morisita, M. Measuring of the dispersion and analysis of distribution patterns, Memoires of the Faculty of Science,...
Globally, 296 million people are infected with hepatitis B virus (HBV), and approximately one million people die annually from HBV-related causes, including liver cancer. Although there is a preventative vaccine and antiviral therapies suppressing HBV re
and formation of hepatitis B surface antibody (anti-HBs), allowing patients to achieve durable immunity with REP 9 AC and its modified form [94,95]. In a study of 12 HBeAg-positive CHB patients, the NAP HBsAg release inhibitor REP2139-Ca was given for 20–38 weeks, with response defined...
Vaccinated: One man’s quest to defeat the world’s deadliest diseases Smithsonian Books, New York (2007) Google Scholar Orsenigo, 1989 L. Orsenigo The emergence of biotechnology: Institutions and markets in industrial innovation Pinter, New York (1989) Google Scholar Pasek et al., 1979 M. Pas...