assay on the device, but by using a solution of standard analytes with predetermined concentrations in place of blood sample. Day-to-day results from running the assay on this standard solution on the device should remain consistent. Lastly, our device is inexpensive relative to current diagnostic...
Insights into the immunopathogenesis of chronic HBV infections are fundamental in the quest for novel treatment approaches aimed at a functional cure. While much is known about the ineffective HBV-specific T-cell responses that characterise persistent HBV replication, B cells have been left largely und...
Vaccinated: One man’s quest to defeat the world’s deadliest diseases Smithsonian Books, New York (2007) Google Scholar Orsenigo, 1989 L. Orsenigo The emergence of biotechnology: Institutions and markets in industrial innovation Pinter, New York (1989) Google Scholar Pasek et al., 1979 M. Pas...
The cells were subsequently run on a fluorescent activated cell sorting instrument (Becton Dickinson, San Diego, CA) and analyzed using Cell- Quest software. Cells were gated on live peripheral blood lymphocyte population identified by forward- and side-scatter parameters, and...
Comparative analysis of human and mouse immunoglobulin variable heavy regions from IMGT/LIGM-DB with IMGT/HighV-QUEST. Theor Biol Med Model 11, 30 (2014). Article Google Scholar Morisita, M. Measuring of the dispersion and analysis of distribution patterns, Memoires of the Faculty of Science,...
A diverse B-cell repertoire is essential for recognition and response to infectious and vaccine antigens. High-throughput sequencing of B-cell receptor (BCR) genes can now be used to study the B-cell repertoire at great depth and may shed more light on B
and formation of hepatitis B surface antibody (anti-HBs), allowing patients to achieve durable immunity with REP 9 AC and its modified form [94,95]. In a study of 12 HBeAg-positive CHB patients, the NAP HBsAg release inhibitor REP2139-Ca was given for 20–38 weeks, with response defined...
Populations of cells containing subdiploid DNA content were quantified according to the DNA contents of the cell using Becton–Dickinson Cell Quest software. An average of 104 cells was used in each experiment. Caspase assays Caspase 3 and 8 activities were assayed using calorimetric substrates of ...
C4 QUEST studies [FDA approved (GT-1)] D1 Study AI444040 (GT1,2,3,4) FDA-approved GT-1,GT-3 D2 Daclatasvir NS5A 60 mg EMCUPc (GT1,2,3,4)-ALLY-1 (GT-1)d D4 COMMAND-4 Paritaprevir NS3 150 mg E1e Ritonavir CY450 100 mg PEARL-1 (GT4) , RUBY-1 (GT1) Ombitasvir...
VDJ gene segments were identified and aligned using IMGT/HighV-QUEST41. VDJ sequences were extracted to construct a personal immunoglobulin amino acid sequence library for MS/MS database search. Protein identification and quantification were performed using MaxQuant9. The intensities of iTRAQ ...