heme-containing enzymespromiscuous enzymesThe design of biocatalysts is a goal to improve the rate, selectivity, and environmental friendliness of chemical processes in biotechnology. In this regard, the use of computational techniques has provided valuable assistance in the design of enzymes with ...
et al. Hydroxytryptophan biosynthesis by a family of heme-dependent enzymes in bacteria. Nat Chem Biol 19, 1415–1422 (2023). https://doi.org/10.1038/s41589-023-01416-0 Download citation Received27 November 2022 Accepted03 August 2023 Published31 August 2023 Issue DateNovember 2023 DOIhttps:/...
Comparing to the representatively industrial strain of Trichoderma reesei QM6a, T. asperellum T-1 showed more robust growth, stronger spore production, faster secretion of lignocellulose-decomposing enzymes and better pH tolerance. The reducing sugar released by strain T-1 on the second day of ...
The peroxidase-catalyzed nitration of tyrosine derivatives by nitrite and hydrogen peroxide has been studied in detail using the enzymes lactoperoxidase (L... L Casella,E Monzani,R Roncone,... - 《Environ Health Perspect》 被引量: 66发表: 2002年 加载更多研究...
The Mn(II)-dependent reactivation observed in POD has also been reported in homoprotocatechuate 2,3-dioxygenase, a homologous enzyme to catechol 2,3-dioxygenase, suggesting a similar mechanistic behavior between the enzymes25. As shown in Fig. 4, a sequence alignment search demonstrated that ...
Models for α-ketoacid-dependent nonheme iron enzymesdoi:10.1016/0162-0134(93)85163-3Yu-Min ChiouLawrence QueJournal of Inorganic BiochemistryChiou Y M,Que L Jr. Model Studies of a-Keto Acid-Dependent Nonheme Iron Enzymes: Nitric Oxide Adducts of [FeⅡ(L)(O2CCOPh)](ClO4) complexes....
There is accumulating evidence to show that Nrf2 is a key transcriptional factor that activates the antioxidant-reactive element (ARE) and in turn regulates the expression of antioxidant phase II detoxifying enzymes. It is interesting to note that the promoter region of ho-1 gene contains the ARE...
Multilevel molecular modelling of structure-function relationships in enzymes The binding of the substrate contributes to the stabilization of the structure of the full enzyme complex [17]. The conformational changes influence the ... W Singh 被引量: 0发表: 2016年 The Pseudomonas aeruginosa nirE ge...
Fe(II)- and α-ketoglutarate (α-KG)-dependent dioxygenases are a large and diverse superfamily of mononuclear, non-heme enzymes that perform a variety of ... Zhaoyong Yang,Xiuling Chi,Masanori Funabashi,... - 《Journal of Biological Chemistry》 被引量: 35发表: 2011年 Probing the Iron−...
Hydroxytryptophan biosynthesis by a family of heme-dependent enzymes in bacteriaTryptophan hydroxylases have only been known from eukaryotes and are involved in the biosynthesis of serotonin or melatonin. Here, the authors characterize a family of bacterial tryptophan hydroxylases that differ markedly from...