Formation and Properties of [4Fe-4S] Clusters on the IscU Scaffold Protein Rapid and quantitative reductive coupling of two [2Fe-2S]2+ clusters to form a single [4Fe-4S]2+ cluster on the homodimeric IscU Fe−S cluster scaffold p... Kala,Chandramouli,Mihaela-Carmen,... - 《Biochemistry...
US20100009406 Mar 13, 2008 Jan 14, 2010 Isabelle Migeotte Gene sequence coding formyl peptide receptor binding protein; diagnosing cancer, wound bone healing, obesity, acute heart failure, hypotension, hypertension, urinary retention, osteoporosis, restenosis, atherosclerosis, thrombosis, cardiovascular, ...
HEBP2 (heme-binding protein 2, also known as SOUL) was identified repeatedly in the screen. Such an interaction has been reported in previous screenings (23, 24), but no details of this interaction are available. HEBP2 is distinct from other ALG-2 binding partners in that it lacks a ...
Signal Transduction/Protein Kinases Insulin-Like Growth Factor I Vacuolar ATPase Introduction Cancer cell invasiveness is associated with increased expression of components of the endocytic trafficking machinery (1, 2), and altered trafficking of growth factor receptors and integrins may have a profound ef...
However, the influence of the H-NOX protein on HisKa autophosphorylation has not been evaluated. This process may be important for persistence and pathogenicity in this organism. Here, we have expressed and purified the V. cholerae HisKa (HnoK) and H-NOX in its heme-bound (holo) and ...
Differential protein expression profiles of the hIDO1-, hIDO2- and hIDO1-2-expressing stable cell lines and implications for cell survival We compared the protein profiles of cells expressing either hIDO1 or hIDO2 with those co-expressing hIDO1 and hIDO2 (hIDO1-2) to evaluate the effect of...
Type-2-packing is mostly confined to the OxdA family members and a group of non-heme-binding ferredoxin α + β barrel proteins typi- fied by the hypothetical protein YqjZ (PDB identifier 2GO8) (Fig. 2b). Interestingly, YqjZ-like proteins (PDB identifiers 2GO8, 2FB0, 4NPO) are ...
namelyeme.ecenttudiesf Irrromhe N-2-fixingymbionthizobium leguminosarum (Irr(Rl))howedhat itindseme withubmicromolarffinitytis-Xxx-His (HxH)otif.hisausedhe proteino dissociaterom itsognate DNAegulatory ironontrol elementoxequences,husllowing expressionf itsarget genesnder iron-repleteonditions....
We report here that neudesin is an extracellular heme-binding protein and that its neurotrophic activity is dependent on the binding of heme to its cytochrome b5-like heme/steroid-binding domain. At first, we found that at least a portion of the purified recombinant neudesin appeared to bind ...
To further characterize the function and mechanism of action of the DUOX peroxidase-like domain, the N-terminal region of DUOX1 was expressed and purified from a baculovirus system. Evaluation of this protein demonstrated that it binds heme covalently and exhibits a modest peroxidase activity. ...