Overall, our data indicate that HRG-1 is the first known heme-binding protein that regulates function of the V-ATPase in endosome acidification and trafficking of receptors essential for cell metabolism. MATERIALS AND METHODS General Reagents and Antibodies IGF-I was from PeproTech Inc. (Rocky ...
Structural superimposition of DUF1794 (2FR2) (orange) and its homologue Nitrophorin-like heme binding protein (2A13) in heme unbound form (green).Balasubramanian, LakshmiMadhulika, MishraNarayanaswamy, SrinivasanGovindaraju, Archunan
Recently, members of this large protein family were shown to be involved in heme biosynthesis in Gram-positive bacteria, and thus the protein was renamed HemQ in these organisms. In the present work the structural and heme binding properties of the chlorite dismutase-like protein from the Gram-...
Ikeyama Y, Tasaka M, Fukaki H (2010) RLF, a cytochrome b 5 -like heme/steroid binding domain protein, controls lateral root formation independently of ARF7/19-mediated auxin signaling in Arabidopsis thaliana . Plant J 62:865–875Ikeyama, Y., Tasaka, M. and Fukaki, H. (2010) RLF, a...
Some Gram-positive bacterial pathogens harbor a gene that encodes a protein (HNS, Heme domain of NO Synthase-like proteins) with striking sequence identity to the oxygenase domain of mammalian NO synthases (NOS). However, they lack the N-terminal and the Zn-cysteine motif participating to the ...