Structural superimposition of DUF1794 (2FR2) (orange) and its homologue Nitrophorin-like heme binding protein (2A13) in heme unbound form (green).Balasubramanian, LakshmiMadhulika, MishraNarayanaswamy, SrinivasanGovindaraju, Archunan
Overall, our data indicate that HRG-1 is the first known heme-binding protein that regulates function of the V-ATPase in endosome acidification and trafficking of receptors essential for cell metabolism. MATERIALS AND METHODS General Reagents and Antibodies IGF-I was from PeproTech Inc. (Rocky ...
Recently, members of this large protein family were shown to be involved in heme biosynthesis in Gram-positive bacteria, and thus the protein was renamed HemQ in these organisms. In the present work the structural and heme binding properties of the chlorite dismutase-like protein from the Gram-...
Ikeyama Y, Tasaka M, Fukaki H (2010) RLF, a cytochrome b 5 -like heme/steroid binding domain protein, controls lateral root formation independently of ARF7/19-mediated auxin signaling in Arabidopsis thaliana . Plant J 62:865–875Ikeyama, Y., Tasaka, M. and Fukaki, H. (2010) RLF, a...
Hemophore-like proteinHeme transfer mechanismBacterial pathogenesisPorphyromonas gingivalisacquires heme as iron and protoporphyrin IX source.HmuY hemophore-like protein is a main Hmu heme uptake system component.Binding the gaseous ligands to HmuY-heme suggests the basis of heme release.Heme release from...