heart disease endpoints The chromosome 9p21 region: mechanistic clues and candidate genes Genome-wide association studies of plasma lipids: new loci "Mendelian randomization" studies: using genetics to identify causal emerging risk factors Genetic testing in coronary heart disease: ready for "prime time...
Genetics of Congenital Heart Disease: Is the Glass Now Half-Full? Congenital heart defects are present in 1% of all live births and are a significant burden on the parents and family, healthcare system, and overall commun... L Leatherbury,CI Berul - 《Circulation Cardiovascular Genetics》 被...
Coronary heart disease (CHD) is the single leading cause of death in America, accounting for about one of every five deaths [1]. Family history of premature parental CHD is associated with a twofold increased risk of cardiovascular disease, making it vital that providers know their patients' ...
The impact of genetic attribution on stigma associated with rheumatic heart disease in the Western Cape, S... Does genetics matter for disease-related stigma? The impact of genetic attribution on stigma associated with rheumatic heart disease in the Western Cape, ... Faure, Marlyn C.Matshabane...
The section addressing methods of examination in genetics briefly defines cytogenetic and molecular genetic methods of diagnosis. This is followed by a section covering genetics of congenital heart disease, with examples of chromosomal aberrations resulting in the most frequent types of congenital heart ...
of which 72 were not associated with left heart structures. Loci were found near genes previously linked with congenital heart disease, includingNKX2-5,TBX5/TBX3,WNT9BandGATA4. A genome-wide polygenic predictor of right ventricular ejection fraction was associated with incident dilated cardiomyopathy...
Learning you have heart disease might rock your world. Whether your diagnosis is the result of inescapable genetics, long-standing habits, or more likely a little of both, you will probably need to make some big changes in order to improve your heart health and live a longer, more comfortabl...
CRISPR–Cas9 is a versatile tool for recognizing a specific genomic sequence and inducing a double-strand break (DSB) in the DNA.doi:10.1038/nrcardio.2017.128LimGregory BNature Reviews CardiologyLim GB (2017) Gene therapy: Human genome editing in heart disease. Nat Rev Genet 18:580....
The impact of genetic attribution on stigma associated with rheumatic heart disease in the Western Cape, S... Does genetics matter for disease-related stigma? The impact of genetic attribution on stigma associated with rheumatic heart disease in the Western Cape, ......
Genetics and Family History Heart disease tends to run in the family. Did your dad develop heart disease before the age of 55 or your mom before she turned 65? If so, your own risk is higher than normal because one or both of your parents may have passed along a genetic variation that...