In this study, we used Beegle and KEGG pathway databases and two online services for gene prioritization and analysis of genes related to heart disease.Results: Over 200 genes and 5 key signaling pathways related to human heart diseases were found. The processes in which gene mutations trigger ...
Professor Kovacic hopes the findings will invigorate research in the area and will lead to a whole new field of critical work related to heart attacks. Professor Kovacic says, "This knowledge will allow us to go after these really critical genes that cause heart attacks, as we now know just ...
Doctors have long noticed that heart attacks tend to spike around certain times, such as the winter holidays, but the reasons for this are not well understood. Less reported are any trends in heart attacks or othercardiac eventsaround major elections and sporting events. This study is the first...
C.They think it could lead to designer babies and increased inequality. D.They worry that it could make parents abandon children with birth defects. 3. What was the first successful example of human embryo gene editing? ___ A.A genetic mutation related to heart disease was removed by scient...
Across the 46 genes identified by revTWMR, we observed a clear trend for functional relevance. Genes perturbed by complex diseases seem to confirm several previously reported associations between immune-related genes (TRBV) and RA27. In addition, revTWMR allowed gaining insight into the regulatory...
The goal of this study is to identify genes specifically related to the heart physiology. However, this organ is a muscle, and is likely to share similar gene expression with other muscles. The protocol we used to identify heart-specific genes involved the comparison of EST frequencies computed...
strategy highlighted the differential role of immune functions between the RV and LV in the developing heart. Comparatively, RNA-seq analysis of data from C57Bl6/J mice hearts collected at E14 resulted in the enrichment of similar processes related to T cells and leukocyte migration and activation...
A common polymorphism at codon 192 in the human paraoxonase (PON) 1 gene has been shown to be associated with increased risk for coronary heart disease (CHD) in Caucasian populations. However, these findings have not been reported consistently in all Caucasian and non-Caucasian populations, sugges...
Expression ofZfp45Lwas almost null in strains with a lower stroke risk (i.e., SHR and SHRSPrch1_18). Because the zinc-finger family proteins are thought to function as a transcriptional regulator, genes regulated byZfp45Lmight be causally related to stroke. Although the human orthologZNF45was...
A new study suggests that genes may not be to blame for the increased risk of heart disease some studies have shown in people with migraine, especially those with migraine with aura. The research is published during Headache/Migraine Awareness Month in the inaugural issue of the journal ...