Genetic Factors in Coronary Heart Disease. Kluwer Acad Publ; 1994. Familial clustering of coronary heart disease: a review of the significance and role as a risk factor for the disease; pp. 37–53.Goldbourt U, De Faire U, Berg K. Genetic Factors in Coronary Heart Disease. Dordrecht/...
Congenital heart defect (CHD) (先天性心脏病), also known as a congenital heart anomaly or congenital heart disease, is a problem in the structure of the heart that is present at birth. It may caused by genetic or environmental factors, or ...
LA JOLLA, California — The use of genetic sequencing to identify which patients would benefit most from aggressive statin therapy for the primary prevention of a heart attack could soon be a clinical reality. And the discovery of genetic mutations associated with cardiovascular disease — but not ...
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Whereas most genetic studies cited already in this report aim to explain altered form and function of the heart with a single strong genetic factor, other studies have searched for more common variants, which could influence susceptibility for certain disease traits. As opposed to Mendelian models,...
“Hundreds of genetic factors affecting the risk of developing cardiovascular diseases have already been identified. However, the number of known variants that reduce the risk of disease and directly indicate the active gene, like theMFGE8variant, is relatively low,” says Doctoral Researcher Sanni ...
. Recent studies suggest a role of small non-coding RNAs, micro RNA, in congenital heart disease. The recently described epigenetic factors have also been found to contribute to cardiac morphogenesis. In this review, we present past and recent genetic discoveries in congenital heart disease....
Although genetic factors contribute significantly to cause CHD, specific genetic lesions are unknown for most patients. The National Heart, Lung, and Blood Institute-funded Pediatric Cardiac ...
Heart disease is the primary cause of morbidity and mortality around the world, with coronary artery disease, diabetes and obesity being major contributing factors. Changes in heart shape and function are known to characterize the progression of disease. Many studies now rely on non-invasive cardiac...
1. Strengthen health care during pregnancy, supplement adequate folic acid in the early stage of pregnancy, actively prevent viral diseases such as rubella and influenza, avoid contact with factors related to the disease, and maintain a healthy lifestyle.2. Activities and rest formulate a reasonable...