三种不同的ASO有效地阻断了肝脏HAND2-AS1的表达,但不能阻断ASO的扰乱对照(图2J),此外,HAND2-AS1 ASOS给药显着降低了肿瘤的生长(图2K)。HAND2-AS1的过表达显著增加了肿瘤圈的形成(图2L),图M,N为在一系列有限稀释法移植过程中HAND2-AS1过表达和对照HCC细胞中TIC的估计频率。HAND2-AS1的过表达显著增强了Huh...
口腔鳞癌表达临床意义目的:检测口腔鳞癌患者中长链非编码RNA HAND2-AS1(lncRNA HAND2-AS1)和葡萄糖转运蛋白-1(GLUT-1)的表达情况,并探究两者与患者病理特征及预后的关系.方法:选取本院口腔科经病理检查确诊为口腔鳞癌患者68例,取其手术切除的口腔鳞癌组织和癌旁正常组织,采用实时荧光定量PCR法(qRT-PCR)分别检测癌...
Figure 1 LncRNA HAND2-AS1 was down‐regulated in prostate cancer. Notes: (A) The expression level of HAND2-AS1 was decreased in PCa tissues compared with adjacent tissues. (B) The expression level of HAND2-AS1 was down‐regulated in PCa cell lines compared with normal cells. *...
et al. Retraction Note to: lncRNA HAND2-AS1 is downregulated in osteoarthritis and regulates IL-6 expression in chondrocytes. J Orthop Surg Res 17, 313 (2022). https://doi.org/10.1186/s13018-022-03206-1 Download citation Published14 June 2022 DOIhttps://doi.org/10.1186/s13018-022-...
In conclusion, a lncRNA HAND2AS1/miR106a/PTEN axis that resensitizes DDPresistant SKOV3/DDP cells to DDP treatment has been established. 展开 关键词: PTEN cisplatin‑resistance long non‑coding RNA HAND2‑AS1 microRNA 106a ovarian cancer ...
关键词: LncRNA HAND2-AS1 HAND2 NMU Promoter hypermethylation Endometrial carcinoma EEC Endometrioid endometrial carcinoma lncRNAs long noncoding RNAs NE normal endometrium HAND2 Heart and Neural Crest Derivatives Expressed 2 NMU neuromedin U DOI: 10.1016/j.canlet.2017.10.028 被引量: 5 ...
目的探究长链非编码RNA(LncRNA)心脏和神经嵴衍生物表达转录本2反义序列1(HAND2-AS1)在宫颈癌患者血清中的表达及其临床意义.方法选取2019年1月至2020年6月焦作市妇幼保... 张晓科,褚艳荣,崔发财 - 《现代医药卫生》 被引量: 0发表: 2024年 转录因子Hand2在妊娠期糖尿病胎鼠心脏发育过程中的表达 目的:了解妊...
Meta分析目的 通过Meta分析评估血液中lncRNA HAND2反义RNA1(HAND2-AS1)的表达水平对多种肿瘤的临床诊断价值.方法 由两名评价员利用计算机检索PubMed,Embase,SinoMed和万方等数据库,检索时限为1980年1月1日至2020年9月30日,收集国内外公开发表有关HAND2-AS1表达水平与肿瘤癌症相关的所有文献,采用STATA 14.0软件对...
Objective To investigate the expression and clinical significance of long non-coding RNA (lncRNA) heart and neural crest derivatives express transcript 2 antisense sequence 1 (HAND2-AS1) in serum of patients with cervical cancer. Methods A total of 50 patients with...
lncRNA HAND2‐AS1migrationmiRNA‐21proliferationLong noncoding RNA (lncRNA) HAND2〢S1 is a wellヽharacterized tumor suppressor in several types of malignancies, while its role in esophagus squamous cell carcinoma (ESCC) is unknown. In this study, we found that lncRNA HAND2〢S1 was ...