LncRNA LIPE-AS1, highly expressed in PCOS exosomes, was related to a poor oocyte maturation and embryo development in PCOS patients. Reduced number of MII oocytes were observed in the LIPE-AS1 group by in vitro maturation (IVM) experiments in mouse. LIPE-AS1 was also shown to modulate ...
越来越多的研究表明,长链非编码 RNA (lncRNA) 有助于宫颈癌 (CC) 的发展。然而,LIPE-AS1 的作用仍有待在 CC 中进行研究。 2021年4月9日,南京医科大学傅士龙及程文俊共同通讯在Frontiers in Oncology(IF=6.24)在线发表题为“LncRNA LIPE-AS1 Predicts Poor Survival of Cervical Cancer and Promotes Its Prolif...
The OB-DHA network featured only eight nodes and had only the DEL LIPE-AS1 with a degree > 5. Finally, the interactome for the CRC-AA condition included 19 nodes, with only two DELs having a degree > 5, whereas 10 nodes were present in the CRC-DHA network, with a prevalent role of...
Expression of lipid metabolic-related genes LIPE, REEP6, GABRE, FBP1, SCD1, UGT2B11, APOC1 was confirmed by RT-qPCR. Functional analysis demonstrated that the knockdown of SOX9-AS1 increases the triglyceride synthesis, cell migration and invasion in both two TNBC cell lines. In conclusion, ...