We performed a Bayesian Analysis and Markov Chain Monte Carlo Method with GTSF1 levels of expression reported on The Cancer Genome Atlas (TCGA), which confirmed high levels of mRNA in lymphomas. Nonetheless, the role of GTSF1 in retrotransposon control in cancer and in carcinogenesis remains ...
This work was performed with assistance from the CSHL Next-generation Sequencing, Sequence Technologies and Analysis, and Mass Spectrometry Shared Resources, which are supported by the Cancer Center Support Grant 5P30CA045508. Cryo-EM was performed at the CSHL cryo-EM facility. OSS cells, medium ...
Although not officially a Cancer-Testis (CT) antigen, ectopic expression of Gametocyte Specific Factor 1 (GTSF1), presents the same advantages than CT antigens. Its germline-cell restricted expression potentially makes this gene easily identifiable by the immune system and a therapeutic target with...