Discussion of the neutrophil marker Ly6G/Gr1, which is readily detectable on mouse eosinophils, and is expressed in higher levels in the presence of IL-5.2020 Society for Leukocyte Biology.doi:10.1002/JLB.2CE1119-473RPaige LacyAlberta Respiratory Centre, Department of Medicine University of Alberta...
Here, we characterize an eosinophil sub-population defined by high levels of expression of the neutrophil Ag Gr1 (CD45(+)CD11c(-)SiglecF(+)Gr1(hi)). SiglecF(+)Gr1(hi) eosinophils, distinct from the canonical SiglecF(+)Gr1(-) eosinophil population, were detected in allergen-challenged wild...
Extensive chemotactic assays proved that CXCL17-responding cells were CD11b+Gr1highF4/80−cells (∼90%) with a neutrophil-like morphologyin vitro. Although CXCL17 expression could not increase the number of CD11b+Gr1+cells in tumor-burdened SCID mice or promote metastases of low metastatic ...
Here, we characterize an eosinophil subpopulation defined by high levels of expression of the neutrophil Ag Gr1 (CD45+CD11c-SiglecF+Gr1hi). SiglecF+Gr1hi eosinophils, distinct from the canonical SiglecF+Gr1- eosinophil population, were detected in allergen-challenged wild-type and granule protein-...
Extensive chemotactic assays proved that CXCL17-responding cells were CD11b+ Gr1high F4/80- cells (~90%) with a neutrophil-like morphology in vitro. Although CXCL17 expression could not increase the number of CD11b+ Gr1+ cells in tumor-burdened SCID mice or promote metastases of low ...