The effects of ectoenzyme activity on cell function have often seemed independent of GPI signaling.Ian OkazakiJoel MossPNH and the GPI-Linked ProteinsOkazaki, I., and Moss, J. 2000. The function of GPI-anchored proteins. In PNH and the GPI-linked proteins. N.S.Young and J. Moss, ...
The protein product of the CpGap1 gene is the first GPI-AP of C. parasitica investigated to date. Our study of the GPI-AP clearly demonstrates the molecular mechanism of the phytopathogenic fungal GPI-AP as a virulence factor. In addition, the function of the cell wall anchored protein ...
GPI锚定蛋白的细胞膜修饰功能研究新进展5摘要:GPI锚定蛋白GPI-anchored proteinGPI-AP是一类通过其羧基末端的糖基化磷脂酰肌醇 glycosylphosphatidy-l-inositolGPI结构锚定于真核细胞膜表面的蛋白。GPI-AP最大 的特点是没有跨膜区和胞内部分,不跨越细胞膜脂质双层,只通过其羧基末端的 GPI结构锚定于细胞膜上。本文...
·anchoredproteinre— GPI—anchoredproteinsisrequiredfortheirraftassociation[J]. leaseassociatedwithlipid raftreorganizationnadacrosomereac— MolecularBiologyoftheCell,2007,18:1497～1506 tiontoacquirefertility[J].CellScience,2011,124(15):2573 [9] TanakaS,MaedaY,TashimaY,eta1.Inositoldeacylationofglyco·...
临床医学论文:GPI锚定蛋白的细胞膜修饰功能研究新进展 GPI-anchored protein function of the cell membrane modification research progress 热度: 含GPI锚定区的膜表面蛋白 热度: 流式细胞术检测GPI锚定蛋白在PNH患者诊断 热度: 相关推荐 6JournalofLipidResearchVolume57,2016 Copyright©2016bytheAmerican...
The basic structure of a GPI-anchored protein consists of phosphatidylinositol (PI) linked to an unusual non-N-acetyl glucosamine, which, in turn, is linked to three mannose residues followed by an ethanolamine covalently linked to the protein via an amide linkage (EtNP-6Manα1-2Manα1-6...
Proteins that were previously shown to be required for tethering and fusion of ER-derived vesicles with the Golgi compartment have been shown to have an additional function in GPI-anchored-protein sorting. GPI-anchored proteins are found in very small microdomains at the plasma membrane. They can...
GPI-anchored proteins are organized in submicron domains at the cell surface. Nature 394, 798–801 (1998). 30. Suzuki, K. G. et al. Transient GPI-anchored protein homodimers are units for raft organization and function. Nat. Chem. Biol. 8, 774–783 (2012). 31. Brameshuber, M. et...
Sorting GPI-anchored proteins. The study of glycosylphosphatidylinositol-anchored-protein sorting has led to some surprising new findings and concepts. Evidence is accumulating that, dur... S Mayor,H Riezman - 《Nat Rev Mol Cell Biol》 被引量: 689发表: 2004年 Sorting GPI-anchored proteins. The...
GPI-anchored proteins are ubiquitously distributed among Eucarya from vertebrates to protozoa, and also shown to be present in some of Archaeobacteria such as Sulfolobus. There is no evidence for the presence of CPI-anchored protein in Eubacteria. In the eucaryotic cells, both biosynthesis of GPI...