GLP-1–estrogen also reduced food intake and weight gain, and improved glucose control and glucose tolerance when compared with GLP-1 alone.doi:10.1038/nrendo.2014.242NoneNature Reviews Endocrinology
Glucagon-like peptide-1 (GLP-1) is an incretin peptide hormone mainly secreted by enteroendocrine intestinal L-cells. GLP-1 is also secreted by α-cells of the pancreas and the central nervous system (CNS). GLP-1 secretion is stimulated by nutrient intake and exerts its effects on glucose h...
3 GLP-1/Estrogen Anti-diabetic, Anti-obesity Leptinomimetic effects through modulation in hypothalamic feeding circuit Produce side effects on endocrine reproductive system and unwanted mitogenic capecity db/db mice and DIO mice [89] 4 GLP-1/glucagon Anti-diabetic, Anti-obesity Promote hepatic lipol...
Glucagon-like peptide-1 (GLP-1) is an incretin peptide hormone mainly secreted by enteroendocrine intestinal L-cells. GLP-1 is also secreted by α-cells of the pancreas and the central nervous system (CNS). GLP-1 secretion is stimulated by nutrient intake and exerts its effects on glucose h...
Deletion of leptin receptors in vagal afferent neurons disrupts estrogen signaling, body weight, food intake and hormonal controls of feeding in female mice. Am. J. Physiol. Endocrinol. Metab. 2019, 316, E568–E577. [Google Scholar] [CrossRef] Grabauskas, G.; Wu, X.; Zhou, S.; Li, ...
1. Can GLP-1 medications improve sex life through weight loss? Yes, GLP-1 medications can improve your sex life by promoting weight loss, which enhances body image, self-esteem, and hormonal balance. These factors contribute to a more satisfying and enjoyable sexual experience. ...
GLP-1RA (such as exendin-4) treatment can reduce the size of MI impacted cardiac volume in rats, inhibit ventricular dilation, myocardial fibrosis and hypertrophy in vivo [72]. Mechanically, GLP-1RAs regulate insulin-like growth factor-1/2 and upregulate α-estrogen receptors to exert ...
In addition, GLP-1 RAs regulate insulin-like growth factor-1/2 and promote the expression of α-estrogen receptor, which can also decrease drug-induced myocardial injuries and provide cardiac protection in patients on isoprenaline [110]. However, a number of clinical trials in patients with HF ...
Estrogen (E) has been identified in epidemiologic and prospective studies to protect against the development of cardiovascular disease in women. It is uncl... Morey Anjali K.,P Ali,R Mahnaz,... - 《Endocrinology》 被引量: 322发表: 1997年 ...
1/GLP-1 signaling could result in neuroprotection and neurotrophic effects for the clinical-pathological presentation of ALS and other brain diseases. Thus, the potential benefits of IGF-1/GLP-1 signal upregulation in the development of disease-modifying therapeutic strategies may prevent ALS and ...