Use of restorative and adaptive immunotherapies with different BRMs, cytokines, tumor vaccines, site directed therapies with molecular blocking agents are now practiced to combat with glioma and still no major breakthrough has been obtained to extend life expectancy significantly. In our laboratory a ...
Glioblastoma is detrimental brain tumor with less than 2 years of life expectancy. They are refractory to conventional therapy and show high relapse rate. GBM tumors exhibit diverse intra-tumoral hete 展开 关键词: Glioblastoma Glioma stem-like cells Therapy resistance Neurosphere Temozolomide Radiation...
The most common of primary brain tumor is generally associated with very high rates of mortality (ca. 90%) and low survival (about 1 year). Moreover, glioma have a poor prognosis and limited treatment options. The reference drug is temozolomide (TMZ) which only increases the patients' life...
The impact of rat neurogenic progenitor cells supernatant (RPNS) on the cytotoxic function of lymphocytes in rats under conditions of physiological norm and experimentally modeled tumor (brain glioma strain 101.8) was studied. The research was carried out in animals with inoculated tumor without RPNS...
Glioblastoma multiforme comprises the majority of human brain tumors. Patients with glioblastoma multiforme have poor survival rates, with an average life expectancy of <1 year. To assess possible mechanisms and to potentially target invasive glioma cells, we previously measured the gene expression profil...
Use of restorative and adaptive immunotherapies with different BRMs, cytokines, tumor vaccines, site directed therapies with molecular blocking agents are now practiced to combat with glioma and still no major breakthrough has been obtained to extend life expectancy significantly. In our laboratory a ...
Malignant glioma, or glioblastoma, is the most common and lethal form of brain tumor with a median survival time of 15 months. The established therapeutic regimen includes a tripartite therapy of surgical resection followed by radiation and temozolomide (TMZ) chemotherapy, concurrently with radiation ...
Methods A pilot program of comprehensive palliative care for brain tumor patients was started in the Regina Elena National Cancer Institute of Rome in Octobe... A Pace,V Villani,AD Pasquale,... - 《Neurooncol Pract》 被引量: 16发表: 2014年 High-grade Gliomas: Neuraxis Dissemination Pattern ...
for prognosis prediction, with survival ranging from 1 to 15 years.2 Although various treatment options, including neurosurgical resection and adjuvant chemor adiotherapy, have been explored to prolong the lives of glioma patients, most gliomas exhibit recurrence, thereby reducing life expectancy. No...
12. Medical Research Council Brain Tumor Working P. Randomized trial of procarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma: a Medical Research Council trial. J Clin Oncol 2001;19:509-18. 13. Stewart LA. Chemotherapy in adult high-grade glioma: a ...