The growth inhibition of remote metastases by a primary tumor is known as endogenous growth inhibition leading to tumor dormancy. Such a phenotype has not been described in primary malignant gliomas. However, although glioma cells have frequently spread to other parts of the brain at the time of...
The aim is to showcase a complete change of trends in automated brain tumor models. The paper also covers end to end joint models involving brain tumor segmentation and overall survival prediction. All the methods are probed, and parameters that affect performance are tabulated and analyzed.doi:...
The team tested the system against three different model cells that mimic different grades of malignancy. They explained, “Time-dependent emission spectra of the Eu(III) complexes in various types of tumor cells were recorded. The radiative rate constants (kr), which depend on the geometry of ...
NIC treatment of mice bearing intracranial GL261 glioblastoma (GBM) results in an increase of CD8+ T cells, NK cells and macrophages with a decrease of regulatory T cells (Tregs) in the brain tumor area. Survival of GBM-bearing mice treated with NIC combination is significantly longer compared...
The monitored variables for both groups were the tumor pathohistology (the tumor type), the survival rate (time between surgery and follow-up), and the outcome assessed by The Extended Glasgow Outcome Scale. Data statistical analysis was done to compare various investigated variables in two ...
of serial tumour volumetric measurement at WHO grade 4 glioma first recurrence. We hypothesized that the greater the rate of tumour volume increase prior to surgery at first tumour recurrence, the more likely the patient will have a worse survival and potentially less likely to benefit from ...
which can inhibit tumormetastasisand prolong thesurvival timeof patients. However,glioma cellsshow invasive growth, and the tumor is easy to spread and metastasize, causing damage to the surrounding normal tissue cells. Surgical treatment is difficult to eradicate, with a high recurrence rate. In ad...
The 5-year overall survival rate of patients is less than ten percent.3 To date, the molecular mechanism involved in the development of glioma remains unclear. Therefore, it is necessary to develop new therapeutic strategies and improve the clinical outcome. In recent decades, microRNAs (miRNAs)...
Glioma is the most common and lethal primary brain tumor, accounting for 81% of central nervous system malignancies1. Higher grade glioma is highly invasive and recurrent, with a median survival of 15 months2. The high incidence of the glioma occurs in young and middle-aged adults, bringing ...
(2) The tumor to non-tumor ratios (T/N) were calculated according to ROI and compared between groups of different malignancy grading by t-test. (3) The survival time (by means of mean survival time, MST) after (99)Tc(m)-MIBI brain SPECT was follow-up surveyed. According to T/N ...