Glioblastomas are aggressive brain tumors that affect about half of all people with a brain tumor. There is no cure yet, but there are glioblastoma treatments that can help improve your quality of life and help you live longer. Ongoing research has found newer treatments along with thetraditiona...
Brain tumors are often difficult to remove, because the brain can be damaged easily and does not tend to repair itself as well as some other organs in the body. Therefore, the typical cancer treatments are not usually enough to cure the problem. They can, however, prolong the patient's ...
The brain tumors which are caused due to glioblastoma multiforme are generally malignant in nature and grow aggressively. Young patients suffering from the condition have high chances of survival where as older patents do not have a favorable outcome. Infants born with glioblastoma multiforme have ...
Immunotherapies are important therapeutic alternatives in the management of brain tumors because an effective immune response could eliminate neoplastic cells. Crossing the blood-brain barrier is problematic for many therapies, and this is the same for chemotherapy; however, a few immune syste...
Glioblastoma is detrimental brain tumor with less than 2 years of life expectancy. They are refractory to conventional therapy and show high relapse rate. GBM tumors exhibit diverse intra-tumoral hete 展开 关键词: Glioblastoma Glioma stem-like cells Therapy resistance Neurosphere Temozolomide Radiation...
Glioblastoma is an aggressive brain tumor with an average life expectancy between 14 and 16 months after diagnosis. The Ki-67 labeling index (LI), a measure of cellular proliferation, is emerging as a prognostic marker in GBM. In this study, we investigated the ultrastructure of glioblastoma tis...
In contrast, glioblastoma (GBM) is the most common primary brain tumor in adults. It is a malignant brain tumor that most often occurs in elderly patients, and GBM in young adults or adolescents appears to be rare. Here, we describe our experience of two cases of GBM in young long-term...
(Medical Xpress) -- A recent study from scientists at the Friedrich Miescher Institute for Biomedical Research has identified a novel target for the treatment of malignant brain tumors. The scientists found that the Mer receptor tyrosine kinase (MerTK) i
Glioblastoma (GBM) is a fatal and incurable brain tumor, with an average life expectancy after diagnosis of only 12-15 months. A main reason for the lethality of GBM is inevitable recurrence, caused by a small population of the tumor cells, called cancer stem cells (CSCs). These cells are...
tumors grow in the brain. When BRD8 was inactivated, p53 was unlocked—the tumors stopped growing and the mice lived longer. “Here we identified BRD8 as an epigenetic vulnerability for TP53WTGBM, which to our knowledge has not been previously associated with this brain malignancy,” the...