DA Mitchell,PE Fecci,JH Sampson - 《Cancer Journal》 被引量: 39发表: 2003年 Galectin-1 and immunotherapy for brain cancer The prognosis of patients diagnosed with high-grade glioma continues to be dismal in spite of multimodal treatment. Active specific immunotherapy by means ... Tina,Verschue...
These results suggest direct vaccination with CpG/lysate provides an alternative and effective approach to induce host antitumor immunity and warrants clinical investigation in the immunotherapy of cancer. 展开 关键词: Keywords CpG glioma immunotherapy cancer vaccine in vivo imaging DOI: 10.1097/CJI.0...
Identification of Genes Associated with Cancer Prognosis in Glioma: In Silico Data Analyses of Chinese Glioma Genome Atlas (CGGA) and the Cancer Genome Atl... Identification of Genes Associated with Cancer Prognosis in Glioma: In Silico Data Analyses of Chinese Glioma Genome Atlas (CGGA) and the...
Recent data suggest that progression of these brain tumors is driven by a small subpopulation of tumor cells, which are termed cancer stem cells (CSCs) because of their capability to self-renew, proliferate and give rise to progeny of multiple neuroepithelial lineages. According to the CSC ...
Gliomais the most common primary brain cancer, and half of patients present a diagnosis ofglioblastoma(GBM), its most aggressive and lethal form. Conventional therapies, including surgery, radiotherapy, and chemotherapy, have not resulted in major ameliorations inGBMsurvival outcome, which remains extr...
CONCLUSION: As a noninvasive technique, (99)Tc(m)-MIBI brain SPECT is effective to diagnose brain glioma and distinguish its malignancy degree. This method, by monitoring the T/N ratio closely, is useful to discriminate tumor viability and determine the prognosis of patients. 展开 ...
Glioblastoma multiforme is the most common primary malignant brain tumour, with a median survival of about one year. This poor prognosis is due to therapeu... J Chen,Y Li,TS Yu,... - 《Nature》 被引量: 1815发表: 2012年 Transdifferentiation of glioblastoma cells into vascular endothelial cell...
Despite progress in conventional treatments, the prognosis remains dismal. Recent studies have suggested that a glioma brain tumor may arise from a "cancer stem cell". To understand this theory we summarize studies of the concepts of neural stem cell, and its specialized microenvironment, namely ...
Metastasis-associated protein 3 in colorectal cancer determines tumor recurrence and prognosis Metastasis-associated protein family (MTA) promotes tumor cell invasion and metastasis of human malignancies. However, the novel component of MTA family, M... H Yi,Y Li,F He,... - 《Oncotarget》 被引...
leading to a dismal prognosis. After treatment, survival can only be prolonged for several months, and no cure has been achieved. More than half of the patients died within five years after diagnosis and the cancer had a high recurrence rate after treatment3. The main obstacles to treatment ...