Even among patients with low-grade gliomas that confer a relatively good prognosis, treatment is almost never curative.Surgery and radiation have been the mainstays of therapy for most glioma patients, but temozolomide chemotherapy has recently been proven to prolong overall survival in patients with ...
Treatment of a high-grade glioma includes measures to relieve symptoms and eliminate or control the tumor. This may include surgery, radiation, and/or chemotherapy. (See"Initial treatment and prognosis of IDH-wildtype glioblastoma in adults"and"Radiation therapy for high-grade gliomas"and"Clinical ...
Gliomas represent the most frequent form of primary brain tumors in adults, the prognosis of which remains extremely poor. Inactivating mutations on the tumor suppressor TP53 were proposed as a key etiological trigger of glioma development. p53 has been recently identified as a transcriptional target ...
Glioblastoma (GBM) is the most frequent and aggressive form of primary brain tumors in adults; it is characterized by its resistance to current treatments (surgery, chemotherapy and radiotherapy). The prognosis is grim with a median survival of only 15 months underlining the importance to develop ...
GLIOMACHEMOTHERAPYIDHDiffuse glioma is the most common primary malignant brain tumor in adults.Currently,the prognosis of glioma remains dismal,and almost all patients with glioma experience recurrence even after comprehensive treatment including maximal surgical resection,radiotherapy,and/or chemotherapy1.Glio...
expressed in glioblastoma (GBM). The association of high MYBPH expression with poor prognosis in newly diagnosed GBM patients and increased expression in recurrent GBM is indicative of its role in tumor aggressiveness. Introduction Glioma is the most common primary malignant tumor of the central nervo...
Objective To explore the relationship of Ki67 expression with the clinical stage and prognosis of neuroglioma patients. Methods 114 cases of glioma patient's data from Jan 2013 to Jan 2016 were enrolled in this part. The relationship of Ki67 expression with the clinicalstage and prognosis were as...
The role of Gliadel wafers in the treatment of high-grade gliomas Glioblastoma multiforme (GBM) is the most aggressive brain tumor. Standard treatment includes surgery, radiation and chemotherapy. Prognosis is dismal with... A Bregy,AH Shah,MV Diaz,... - 《Expert Review of Anticancer Therapy》...
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults [1] and carries a grim prognosis. Infiltrative nature of diffuse gliomas makes it difficult to eliminate microscopic disease despite macroscopic gross total resection. Recurrence of GBM is inevitable, and the median overall...
pilocytic astrocytoma pilocytic astrocytoma pilocytic astrocytoma excellent prognosis irrespective of treatment modality distinctly different behavior from diffusely infiltrating gliomas 10-year survival 95% vs 17% in ncctg 86-72-51 diffusely infiltrating glioma surgery radiation chemotherapy surgery usually ...