GFP+ cells with Neurogenin2 expression were largely distributed in the VZ, whereas GFP+ cells with Tbr2 and NeuroD expressions were seen in the migratory stream and developing dentate gyrus. Prox1-expressing GFP+ cells were restricted to the developing dentate gyrus. These results suggest that ...
Ghrelin ameliorates neuronal damage, oxidative stress, inflammatory parameters, and GFAP expression in traumatic brain injuryGhrelintraumatic brain injuryoxidative stressinflammationneuropeptideneurodegenerationSPINAL-CORD MOTONEURONSMECHANISMSBARRIEREXCITOTOXICITYObjectiveThis study investigated the effects of ghrelin on ...
Glial fibrillary acidic protein (GFAP) is a specific astrocyte biomarker protein, which plays an important role in modulating the stability of cytoskeletal structure, maintaining mechanical potential of glial cells, and supporting the neighboring neurons [1, 2]. Increasing findings have suggested that ...
GFAPexpression,identifyingapreviouslyunreportedsignalingcascadethatisimportantinastrogliosisandthephysiological responsefollowingbraininjury. GLIA2013;61:2063–2077 Keywords:calciumwave,JNK,astrogliosis,glialfibrillaryacidicprotein,glialscar Introduction A strocytesarethemostabundantcelltypeinthecentral ...
27、ed the pyramidal neurons and made the pyramidal layer look like a shaped grade. All the above suggested that the GLT-1 expression surrounded pyramidal neurons in the hippocampal CA3 subfield protected the neurons survival the global brain ischemic insult. Key words: brain ischemia;GLT-1;GFAP...
in the superior frontal cortex than in the cerebellum in AD brains, which correlates with more neuropathological changes in the frontal cortex (Lue and Rogers, 1992; Brachova et al., 1993); c) an increased expression of mRNA for ClgB, C3 and C4 in AD brains than in age-matched ...
1.any of numerous organic molecules constituting a large portion of the mass of every life form, composed of 20 or more amino acids linked in one or more long chains, the final shape and other properties of each protein being determined by the side chains of the amino acids and their chem...
Astrocytes express 10 different isoforms of GFAP that differ in the rod and tail domains (PMID: 25726916), which means that they differ in molecular size. Isoform expression varies during the development and across different subtypes of astrocytes. Not all isoforms are upregulated in reactive astroc...
neurons in hippocampus CA3 area indicated that numerical density on area(N-A),volume density(V-V) and the average of grey scale were gradually decreased coincidenced with iodine excess levels,furthermore,statistically significance in 100HI group.GFAP positive astrocytes in hippocampus CA3 area showed...
GFP expression in glia co-localized with anti-GFAP antibodies, but did not co-localize with the neuronal antibodies HuC/D or calretinin in mature neurons. 展开 关键词:Glial fibrillary acidic protein Müller glia Radial glia CNS PNS Zebrafish Transgenic GFP Enteric nervous system Retina ...