Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus O-glycosylation of proteins is initiated by a family of UDP-N-acetylgalactosamine:polypeptide N-acetylgalactos-aminyltransferases (GalNAc-T). In this stu...
Zurawski VR, Orjaseter H, Andersen A, Jellum E (1988) Elevated serum CA 125 levels prior to diagnosis of ovarian neoplasia: relevance for early detection of ovarian cancer. Int J Cancer 42:677–680.Zurawski, VR, Orjaseter, H, Andersen, A, Jellum, E (1988) Elevated serum CA 125 ...
the step where the first glycan is attached to the relevant amino acid residue in the protein, mucin-type O-glycosylation is controlled by a large family of up to 20 homologous genes encoding UDP-GalNAc:polypeptide GalNAc-transferases (GalNAc-Ts) (EC 2.4.1.41). Therefore, mucin-type O-...
Mandel, H. Clausen, et al., Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family, Glycobiology 22 (2012) 736-756.Bennett, E.P.; Mandel, U.; Clausen, H.; Gerken, T.A.; Fritz, T.A.; Tabak, L.A. Control of mucin-type O-...
Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2. Perrine, Cynthia L.,Ganguli, Anjali,Wu, Peng,Bertozzi, Carolyn R.,Fritz, ...
The Initiation of Mucin Type O-glycosylation: Development of a Web-Based Tool for the Prediction of ppGalNAc T Isoform Specific O-Glycosylation 来自 ResearchGate 喜欢 0 阅读量: 19 作者:TA Gerken,G Cardenas,I Almeida,MY Leung 会议时间: 2011/11/01 ...