Inhibition of furin-like enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation. Arthritis Rheum 2003;48:1057-66.Milner JM, Rowan AD, Elliott SF, Cawston TE. Inhibition of furin-like enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation. Arthritis Rheum...
Furin-like Proteasedoi:10.1007/3-540-29832-0_639Furin-like protease is a prohormone convertase, a pro-protein-processing enzyme with cleavage selectivity for paired basic amino acid residues. EndothelinsSpringer Berlin HeidelbergEncyclopedic Reference of Molecular Pharmacology...
How does the polybasic furin-like cleavage site of Bat CoV CD35 compare to that of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)? What differences were observed in the loop structures of the Receptor Binding Domain (RBD) of Bat CoV CD35 compared to SARS-CoV-1 and Severe Ac...
furin-likePCinhibitor,secretionofCFRwasalmostcompletelyinhibited.Secretionwasnotaffectedby theGM6001inhibitor.ThesecretedformswerefurthercharacterizedbycreatingdifferentmutantCFR proteinswithN-terminalandC-terminaltags.Immunoblotanalysisandimmunofluorescenceindicated, ...
5. Furthermore, the Aplysia nucleotide sequence results, together with available sequence information from human, mouse, and Drosophila furins, provide reasonable evidence that the furin-like enzymes may represent a separate subclass of the subtilisin-like processing enzymes. 展开 ...
The furin-like S2′ cleavage site at KR↓SF with P1 and P2 basic residues and a P2′ hydrophobic Phe (Seidah and Prat, 2012), downstream of the IFP is identical between the 2019-nCoV and SARS-CoV (Fig. 2). In the MERS-CoV and HCoV-OC43 the S1/S2 site is replaced by RXXR↓...
The Notch1 receptor is cleaved constitutively by a furin-like convertase The Notch receptor, which is involved in numerous cell fate decisions in invertebrates and vertebrates, is synthesized as a 300-kDa precursor molecule (p30... F Logeat,C Bessia,C Brou,... - 《Proc Natl Acad Sci U S...
Patterning of the Drosophila embryonic termini is achieved by localized activation of the Torso receptor by the growth factor Trunk. Governing this event is the perforin-like protein Torso-like, which is localized to the extracellular space at the embryo
The activating enzyme of the FPV hemagglutinin is furin, a subtilisin-like eukaryotic endoproteaseNo AbstractGarten, W.Vey, M.Stieneke-Groeber, A.Schaefer, W.EXCERPTA MEDICA INTERNATIONAL CONGRESS SERIES
Cleavage of Pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver[J].Journal of Biological Chemistry,1994,(27):18167-... MF Chiron,CM Fryling,DJ Fitzgerald - 《Journal of Biological Chemistry》 被引量: 313发表: 1994年 Regulation of PPAR gamma gene expressio...