Furin-like Proteasedoi:10.1007/3-540-29832-0_639Furin-like protease is a prohormone convertase, a pro-protein-processing enzyme with cleavage selectivity for paired basic amino acid residues. EndothelinsSpringer Berlin HeidelbergEncyclopedic Reference of Molecular Pharmacology...
Furin‐like Proteasedoi:10.1007/978-3-540-38918-7_5740FurinSpringer Berlin HeidelbergEncyclopedia of Molecular Pharmacology
The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin‐like protease(s) in a subpopulation of microgl... The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin‐like protease(s) in a ...
1. Strong evidence is accumulating that the endoproteases which process prohormones at dibasic residue cleavage sites are members of a subtilisin-related class of proteases. 2. Using the polymerase chain reaction (PCR), we have isolated and characterized an Aplysia californica neuroendocrine bag cell...
In the conserved replicase domains, Bat CoV CD35 shared 68.3%–91.5% aa identity in the 3C-like protease (3CLpro) region, 77.0%–93.1% in the RdRp region, and 81.0%–89.2% in the helicase (Hel) region with the corresponding sequences of Bat Hp-betaCoV Zhejiang2013, SARS-CoV-2, ...
A protease, with toxin cleaving activity, was prepared from beef liver and subsequently characterized. After achieving a 500-fold enrichment in several chromatographic steps, a soluble form of this protease was identified as a furin-like enzyme. It cleaved PE on the COOH-terminal side of the ...
substantialproportionofCFRissecretedbuttheunderlyingmecha- nismisunknown.CFRcontainsseveralpossiblefurin-likeproproteinconvertase(PC)andmatrixmetallo- proteinasecleavagesites.CellsexpressingCFRweretreatedwiththefurinproteaseinhibitordecanoyl- Arg-Val-Lys-Arg-chloromethylketone(decCMK)ortheMMP-inhibitorGM6001.Inthe...
A protease, with toxin cleaving activity, was prepared from beef liver and subsequently characterized. After achieving a 500-fold enrichment in several chromatographic steps, a soluble form of this protease was identified as a furin-like enzyme. It cleaved PE on the COOH-terminal side of the ...
Fresh cell pellets were washed twice in milliQ H2O before being ground in 100 μl lysis buffer (50 mM Tris-HCl (pH 7.5), 150 mM NaCl, 2.5 mM EDTA, 0.2% Triton-X, 5% glycerol, complete EDTA free protease inhibitor cocktail (Roche)). For immunoblotting of embryos,∼50 μ...
The activating enzyme of the FPV hemagglutinin is furin, a subtilisin-like eukaryotic endoproteaseNo AbstractGarten, W.Vey, M.Stieneke-Groeber, A.Schaefer, W.EXCERPTA MEDICA INTERNATIONAL CONGRESS SERIES