Furin-like Proteasedoi:10.1007/3-540-29832-0_639Furin-like protease is a prohormone convertase, a pro-protein-processing enzyme with cleavage selectivity for paired basic amino acid residues. EndothelinsSpringer Berlin HeidelbergEncyclopedic Reference of Molecular Pharmacology...
Furin‐like Proteasedoi:10.1007/978-3-540-38918-7_5740FurinSpringer Berlin HeidelbergEncyclopedia of Molecular Pharmacology
In the conserved replicase domains, Bat CoV CD35 shared 68.3%–91.5% aa identity in the 3C-like protease (3CLpro) region, 77.0%–93.1% in the RdRp region, and 81.0%–89.2% in the helicase (Hel) region with the corresponding sequences of Bat Hp-betaCoV Zhejiang2013, SARS-CoV-2, ...
2019-nCoV SARS-CoV Spike protein Maturation protease Furin Antivirals Human coronaviruses (CoV) are enveloped positive-stranded RNA viruses belonging to the order Nidovirales, and are mostly responsible for upper respiratory and digestive tract infections. Among them SARS-CoV and MERS-CoV that spread...
1. Strong evidence is accumulating that the endoproteases which process prohormones at dibasic residue cleavage sites are members of a subtilisin-related class of proteases. 2. Using the polymerase chain reaction (PCR), we have isolated and characterized an Aplysia californica neuroendocrine bag cell...
proteinasecleavagesites.CellsexpressingCFRweretreatedwiththefurinproteaseinhibitordecanoyl- Arg-Val-Lys-Arg-chloromethylketone(decCMK)ortheMMP-inhibitorGM6001.Inthepresenceof furin-likePCinhibitor,secretionofCFRwasalmostcompletelyinhibited.Secretionwasnotaffectedby ...
Fresh cell pellets were washed twice in milliQ H2O before being ground in 100 μl lysis buffer (50 mM Tris-HCl (pH 7.5), 150 mM NaCl, 2.5 mM EDTA, 0.2% Triton-X, 5% glycerol, complete EDTA free protease inhibitor cocktail (Roche)). For immunoblotting of embryos,∼50 μ...
The activating enzyme of the FPV hemagglutinin is furin, a subtilisin-like eukaryotic endoproteaseNo AbstractGarten, W.Vey, M.Stieneke-Groeber, A.Schaefer, W.EXCERPTA MEDICA INTERNATIONAL CONGRESS SERIES
Activation of an Influenza Virus A/Turkey/Oregon/71 HA Insertion Variant by the Subtilisin-like Endoprotease Furin 来自 NCBI 喜欢 0 阅读量: 32 作者:J Morsy,W Garten,R Rott 摘要: The hemagglutinin (HA) gene of the influenza A turkey/Oregon/71 variant Tc1 adapted to primary chicken embryo...
1998 . Identification and characterization of Spodoptera frugiperda furin: A thermostable subtilisin-like endoprotease. Biological Chemistry 379: 1433 – 1440 .Cieplik M, Klenk HD, Garten W. Identification and characteri- zation of Spodoptera frugiperda furin: a thermostable subtilisin- like ...