Inhibition of furinlike enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation . Arthritis Rheum 8 : 1057 – 1066 .Milner JM, Rowan AD, Elliott SF, Cawston TE (2003) Inhibition of furin-like enzymes blocks interleukin-1alpha/ oncostatin M-stimulated cartilage degradation. ...
An isolated chimeric GLP-1 nucleic acid sequence encoding a human pro-insulin leader, a glucagon-like peptide-1 (GLP-1), and a furin cleavable site between the human pro-insulin leader sequence and the GLP-1 is provided. Also provided is an isolated modified chimeric GLP-1 nucleic acid seq...
Inhibition of furin-like enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation. Arthritis Rheum 2003;48:1057-66.J M, Milner,A D,etc.Inhibition of furin-like enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation.[J].2003,48....
To investigate the role of furin-like enzymes in the proteolytic cascades leading to cartilage breakdown and to examine which collagenase(s) contribute to collagen degradation. Bovine nasal cartilage was stimulated to resorb with the addition of interleukin-1伪 (IL-1伪)/oncostatin M (OSM) in the...
Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network. J Biol Chem, 2003. 278(20): 18478-84.Leighton M, Kadler KE: Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network. J Biol Chem 2003, 278(20):18478...
Serpin-like properties of alpha1-antitrypsin Portland towards furin convertase. FEBS Lett 1998; 426: 41-46.Dufour EK, Denault J-B, Hopkins PC, Leduc R (1998) Serpin-like properties of α1-antitrypsin Portland towards furin convertase. FEBS Lett 426(1):41–46. : 10.1016/S0014-...
(1996) Human lactase-phlorizin hydrolase is not processed by furin, PC1/PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1311 , 199-203 Online publication date: 1-May-1996. /...
(1996) Human lactase-phlorizin hydrolase is not processed by furin, PC1/PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1311 , 199-203 Online publication date: 1-May-1996. /...