The development of the cortex is a delicate balance between proliferation, differentiation, and migration of neural progenitors (NPs). Throughout developmental process, various cellular mechanisms ensure that NPs differentiate into the correct cell subtypes, migrate to their correct regions, and form the...
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The duplication of GAPDH seems to have occurred before the evolution of the bilaterian animals (Figure 2B). The liver-specific GAPDH (in vertebrates [42]) is found in all bilaterian species included in this analysis, whereas the testis-specific form occurs only in vertebrates. The tree topology...
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The energy recovered from hydrolysis of succinyl-CoA to succinate may be used for the initial activation of propionate, either in the form of ATP or possibly through direct transfer of CoA by one of several uncharacterized acyl-CoA:carboxylate CoA transferases (Gbem_1430, Gbem_1439, Gbem_...
Therefore, same-read molecular haplotyping gains power with sequencing read length, and the major source of error is the sequencing error rate. Although often overlooked because of its simplicity, sequencing is the most common form of molecular haplotyping. Other forms of molecular haplotyping include...
system. We replaced the gRNA with "GAAGCCATTCAAGGCTGTCAAGG" and obtained the mutant, referring to the study by Gao et al. [15]. According to the genomic analysis results, the mutant contained a frameshift mutation in theDFRgene, and the mutation form contained either deletion of G (Fig....
During male meiosis, the Y chromosome can form perfect pairing with the X chromosome. However, it is unclear whether mammalian Female germline stem cells (FGSCs) without a Y chromosome can transdifferentiate into functional haploid spermatid-like cells (
As in eukaryotes, precursor transfer RNAs in Archaea often contain introns that are removed in tRNA maturation. Two unrelated archaeal species display unique pre-tRNA processing complexity in the form of split tRNA genes, in which two to three segments o