mongolicus, and has been applied in field production [21, 22]. Meanwhile, efficient non-symbiotic nitrogen fixing bacteria also need to be screened, and then combined with symbiotic rhizobia to form a multi-base combined PGPR bacterial agent, thus promoting the nitrogen utilization of Astragalus ...
Apart from ATP synthesis, they are involved in processes such as β-oxidation of fatty acid, calcium homoeostasis, iron transport, and the generation and elimination of reactive oxygen species (ROS). Additionally, mitochondria also play a role in apoptosis, ferroptosis, and inflammasome activation ...
As bypass signaling is a common form of resistance to kinase inhibitors, we sought to identify potential kinases that are activated in ASK120067-resistant cells. We performed a human phospho-RTK array and compared the differential expression of 71 tyrosine kinases in parental and resistant NCI-H197...
Traditional Chinese medicine uses various herbs for the treatment of various diseases for thousands of years and it is now time to assess the characteristics and effectiveness of these medicinal plants based on modern genetic and molecular tools. The her
In eukaryotes, ABC transporters that utilize the energy of ATP hydrolysis to expel cellular substrates into the environment are responsible for most of the efflux from cells. Many members of the superfamily of ABC transporters have been linked with resistance to multiple drugs or toxins. Owing to ...
A well-controlled transition from faster growth rates to theoretically zero growth can be realized via retentostat cultivation, a form of continuous cultivation with full biomass retention. Retentostats are typically initiated from steady-state chemostat cultures. In cases where the energy (and usually...
Metastasis, the spread of a tumor or cancer from the primary site of the body to a secondary site, is a multi-step process in cancer progression, accounting for various obstacles in cancer treatment and most cancer-related deaths. Metabolic reprogramming refers to adaptive metabolic changes that ...
Adenosine monophosphate-activated protein kinase (AMPK) is associated with the development of liver hepatocellular carcinoma (LIHC). AMPKα2, an α2 subunit of AMPK, is encoded by PRKAA2, and functions as the catalytic core of AMPK. However, the role of
cooking quality. Moreover, Mo et al. (2016) found that the spraying of zinc fertilizer could considerably boost the activity of grain proline oxidase, which catalyzed the oxidation of proline to form the precursor substance of 2-AP (Huang et al.2008). Hence, the application of zinc ...
In recent years, immunotherapy has emerged as a promising strategy for treating solid tumors, although its efficacy remains limited to a subset of patients. Transforming non-responsive “cold” tumor types into immuno-responsive “hot” ones is critical