Full isotopologue distributions generated by isotope-tracing MS experiments. Supplementary Video 1 Live imaging of two P5CS-containing mitochondria fusing. Confocal microscopy imaging of a MEF expressing P5CS–GFP (cyan) and mitoDsRed (red) after 3 hours of galactose treatment. Video was acquired ...
Gbelska Y, Subik J, Svoboda A, Goffeau A, Kovac L: Intramitochondrial ATP and cell functions: yeast cells depleted of intramitochondrial ATP lose the ability to grow and multiply. Eur J Biochem 1983, 130 : 281-286. PubMed Abstract Publisher Full Text...
2Fo–Fc electron density map at σ = 1 and fitted crystal structure of theapoform of monomer A (a) and B (b) of ALDH1A3 close to the NAD+-binding and substrate-binding pockets. Full size image Each monomer of the ALDH1A3-NAD+complex at 1.89-Å resolution contains one NAD+mo...
The ABCC subfamily contains 12 full transporters that perform functions in ion transport, toxin secretion, and signal transduction. Cystic fibrosis (CF) is an inherited multisystemic disorder characterized by anormalities in exocrine gland function consequent to loss of function of the CFTR transporter...
2d). Taken together, these results suggest that F-ATPase and VGCC can form a protein complex on the plasma membrane of neutrophils. Table 1 Peptides of VGCCA2D1 identified by BN-PAGE Full size table Fig. 2 F-ATPase/VGCC protein complex verification. a. 1D immunoblot analysis of the ...
He is now a full professor of chemistry in Key Laboratory of Analytical Chemistry for Biology and Medicine (MOE) & College of Chemistry and Molecular Sciences, Wuhan University, China. He is Member of Chinese Chemical Society, Chinese Optical Society and Chinese Society of Micro-Nano Technology....
receptors. Additional residues in the ATP-binding pocket contribute to determining the agonist sensitivity of P2X7 receptors. However, there is still lack of a full understanding of the P2X7 receptors that exhibit a much lower ATP sensitivity and also activation by ATP in the form of ATP4−[4...
Adenosine-5′-triphosphate (ATP) is one of multifunctional nucleotides and plays an important role in cell biology as a coenzyme interacting with proteins. Revealing the binding sites between protein and ATP is significantly important to understand the functionality of the proteins and the mechanisms ...
Full size image In prior experiments, every animal in a given cohort was exposed to the same stressor. We next asked whether animals that had never experienced the teratogen could improve the resistance of conspecifics that were exposed. This would be expected if, for example, animals were provi...
By making the DNA semi-opaque, the thirteen histone-DNA contacts can be visualized (flashing white, and then staying blue) to form a positively-charged staircase along the surface of the octamer, upon which the negatively-charged DNA is wrapped. By unwrapping the DNA, the canonical octamer is...