ZHANG Jiong,WANG Jinquan National Clinical Research Center of Kidney Disease,Jinling Hospital,Nanjing Medical University, Nanjing 210016,China ABSTRACT Focal segmental glomerulosclerosis ( FSGS) is a common glomerular disease leading to end stage renal disease, and podocyte injury is the main cause of ...
2. Haas M, Yousefzadeh N. Glomerular tip lesion in minimal change nephropathy: a study of autopsies before 1950. Am J Kidney Dis 2002; 39:1168. 3. Stokes MB, Markowitz GS, Lin J, et al. Glomerular tip lesion: a distinct entity within the minimal change disease/focal segmental glomerulosc...
摘要: Thromboxane, excreted in the urine in increased amounts in glomerular, vascular and tubulo-interstitial diseases, is considered to originate from the kidney. The localization of thromboxane synthase, a key enzyme of arachidonic acid metabolism, was studied in the human kidney by immunohistology...
Focal segmental glomerulosclerosis (FSGS) is a rare but important cause of end-stage kidney disease in children and adults. Current therapy, consisting of corticosteroids and calcineurin inhibitors, fails to achieve a sustained remission in most patients. Therefore, there is a pressing need to ...
GLOMERULAR-DISEASEOUTCOMESCHILDRENIntroductionFocal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease and can progress to end stage kidney disease (ESKD). An overview of symptoms and impacts of the disease experienced will help inform the selection or development of fit-for-...
Mutations in α-actinin 4 (ACTN4) are linked to familial forms of focal segmental glomerulosclerosis (FSGS), a kidney disease characterized by proteinuria due to podocyte injury. The mechanisms underlying ACTN4 mutant-associated FSGS are not completely understood. Although α-actinins are better ...
kidney biopsy is essential for sound treatment decisions in individual patients. However, it is also essential for the rational design of therapeutic trials in FSGS. Greater recognition of the pathophysiology underlying podocyte stress and damage in FSGS will increase the likelihood that the cause of ...
Microcosmic dysplastic kidney disease CD40L: CD40 ligand rFSGS: Recurrent FSGS LIFRβ: Leukemia inhibitory factor-β CRLF-1: Cytokine receptor-like factor-1 rCASK: Recombinant-CASK WT1: Nephroblastoma protein PEC: Glomerular wall epithelial cell ...
系统标签: fsgs低浓度发性激素回顾对照 硕士学位论文低浓度他克莫司联合激素治疗特发性FSGS的回顾性对照研究刘宝莲指导教师赵洪雯副教授导师组成员彭侃夫教授、刘宏教授、张克勤教授培养单位陆军军医大学第一附属医院肾科申请学位类别临床医学硕士专业学位专业名称内科学(肾脏病)论文提交日期2019年3月论文答辩日期2019年5月答辩...
Pediatric Nephrology - Focal and segmental glomerulosclerosis (FSGS) is the most common glomerular cause of end-stage kidney disease (ESKD). Although the etiology of FSGS has not been fully...Gbadegesin, RasheedBartkowiak, BartlomiejLavin, Peter J....