In order to evaluate the predictive factors of chronic kidney disease (CKD), we retrospectively reviewed the records of 110 children with biopsy-proven FSGS admitted between 1972 and 2004. Renal survival was analyzed by the Kaplan–Meier method and Cox's regression model. Two multivariate models ...
Glomerulonephritis FSGSlt;stronggt;BACKGROUND:lt;/stronggt; Focal segmental glomerulosclerosis (FSGS) is one of the most common glomerulopathies in children leading to end stage renal disease (ESRD). Different values of median renal survival have been reported among different ethnicities and races. ...
the rate of cardiovascular events in 1,912 Canadian patients with biopsy-proven IgA nephropathy, minimal change disease, FSGS, and membranous nephropathy was 2.5 times as high as the general population and was high for each disease type. Consideration of disease type, kidney function, and proteinur...
Third, this study did not include other glomerular diseases related to podocyte lesions such as membranous nephropathy and FSGS, so the clinical value of cofilin-1 as a biomarker of podocyte to predict the renal adverse prognosis of IgAN needs to be further validated. Therefore, future studies ...
Recurrence of FSGS was morphologically documented in 2 recipients 7 and 18 months, respectively, after transplantation. It is concluded that FSGS as the primary disease has a negligible impact on the living-related-donor kidney transplantation in the Egyptian population. Therefore, this disease should...
Membranous nephropathy, focal segmental glomerulosclerosis (FSGS), and minimal change disease (MCD) are the most common causes of idiopathic nephrotic syndrome. For many years prednisone, alkylating agents, and calcineurin inhibitors have been the standard of therapy for these patients. More effective ...
CONCLUSION: Our preliminary findings indicate, for the first time, that positivity for CD44 in PECs seems to be a pathological marker of renal function deterioration in pediatric patients with FSGS. 展开 关键词: Focal segmental glomerulosclerosis Chronic kidney disease Parietal epithelial cells CD44 ...
Primary focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) are common types of primary glomerular disease; they share numerous clinical and pathological similarities but have different treatment regimens and prognoses. It is therefore necessary to distinguish between them and to exp...
Background: In children, focal segmental glomerulosclerosis (FSGS) is one of the most common primary glomerular diseases leading to end-stage renal disease. Exosomes facilitate communication between cells by transporting proteins and microRNAs. We aimed to investigate the utility of urine exosomal miR-...
In general, elevated urinary excretion of NGAL indicated the presence of steroid-resistant disease caused by biopsy-confirmed focal segmental glomerulosclerosis (FSGS) in most of the cases. The authors claim that their findings represent the first description of a simple urine test that could ...