Jacobson, M. (1954) The mode of action of folic acid antagonists and the function of the leuconostoc citrovorum factor Ciba foundation symposion on chemistry and biology of pteridines. Little Brown & Comp., BostonJacobson, M. : The mode of action of folic acid antagonists and the function ...
which can be readily reversed by the addition of folic acid to the diet. An anterior kidney imprint will disclose normal erythropoeisis or the presence of many senile cells in folic acid deficiency. Gross hematology is a simple clinical method for the assessment of folic acid status of the sa...
Folic acid-modified MSN has shown increased drug delivery efficiency to tumors and reduced side effects on healthy cells [19]. Nonetheless, these nano-drug delivery systems are also influenced by the immune system, with reports indicating that less than 0.7 % of intravenously injected nanoparticles ...
The folic acid antagonists enjoy a unique place in cancer chemotherapy (Holland, 1961). Aminopterin was the first designed antimetabolite which provided significant regression of a neoplasm, acute lymphocytic leukemia in children (Farber et al., 1948). Nearly ten years ago, in October 1955, ...
FTIR spectra of NCC, NCC-CTAB, crocin (CR), NCC-CTAB-CR, Folic acid (FA) and NCF-CR-NPs. The diagram shows the transmittance (%) versus wavelength for crystal structures. Full size image FA can interact with the NP surface through its carboxylate groups, forming ionic bonds with positive...
There is evidence that the anticonvulsant action of phenytoin is antagonized by folic acid. A patient whose epilepsy is completely controlled by phenytoin may require increased doses to prevent convulsions if folic acid is given. Folate deficiency may result from increased loss of folate, as in ren...
产品名称:植物叶酸(folicacid)elisa检测试剂盒 品牌:森兴研 规格:96T/48T 保存温度:2-8℃ 保质期:6个月 仅供参考,详细操作请按照订购试剂盒内的说明书操作! ELISA(酶联免疫吸附实验)试剂盒检测抗原或抗体的实验。操作步骤一般包括以下几个步骤: 试剂准备:根据试剂盒说明书将各种试剂准备好,包括抗体、酶标抗体、底...
Mechanism of action of folic acid The mechanism is still being investigated but several positive facts are emerging. Firstly, it seems unlikely that there is a primary folate deficiency. Kirk et aI have shown that mothers carrying foetuses with neural tube defects have a lower Bl2/folate during ...
Folic acid antagonists Previously, folic acid antagonists, which are known to be highly embryolethal, were used in clinical trials as abortifacients (agents causing abortion). Although three-fourths of the pregnancies were terminated, almost one-fourth of the embryos that survived to term were ...
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