The folic acid antagonists enjoy a unique place in cancer chemotherapy (Holland, 1961). Aminopterin was the first designed antimetabolite which provided significant regression of a neoplasm, acute lymphocytic leukemia in children (Farber et al., 1948). Nearly ten years ago, in October 1955, ...
A. Inhibition of bacterial cell-wall synthesis B. Inhibition of bacterial protein synthesis C. Inhibition of bacterial folic acid synthesis D. Inhibition of bacterial DNA gyrase E. Inhibition of bacterial DNA polymerase 相关知识点: 试题来源: 解析 D Inhibition of bacterial DNA gyrase 反馈...
In 1945, 42 patients with pernicious anaemia, were given an oral dose of 30 mg. folic acid three times weekly. Thirty-six returned regularly for observatio... RWCS Vilter,D Horrigan,JF Mueller,... - 《Blood》 被引量: 120发表: 1950年 Why clinical trials of vitamin E and cardiovascular...
Folic acid Folic acid may decrease the excretion rate of Doxycycline which could result in a higher serum level. Fomepizole Doxycycline may decrease the excretion rate of Fomepizole which could result in a higher serum level. Fondaparinux The risk or severity of bleeding can be increased when Doxyc...
Maloney CA, Hay SM & Rees WD (2009) The effects of feeding rats diets deficient in folic acid and related methyl donors on the blood pressure and ... CA Maloney,SM Hay,WD Rees - 《British Journal of Nutrition》 被引量: 33发表: 2008年 Action of sympathomimetic and allied amines on the...
Folic acid Mesalazine may decrease the excretion rate of Folic acid which could result in a higher serum level. Fomepizole Mesalazine may decrease the excretion rate of Fomepizole which could result in a higher serum level. Fondaparinux The risk or severity of bleeding can be increased when Mesalaz...
In the liver of the intact mouse, the conversion of exogenous folic acid to compounds with citrovorum-factor activity is inhibited completely by an amount of amethopterin similar to that bound to the enzyme folic acid reductase in vitro. Because this amount of amethopterin is several thousand ...
This resulted principally in stunting of the root system which could be reversed by the simultaneous addition of either p -aminobenzoic acid or folic acid. Compounds related to p -aminobenzoic acid had no such activity. It is proposed that a possible mechanism of action of asulam is the ...
Action video game for wagering where the player's reward to a challenge is determined by combining the player's skill in facing the challenge with the realization of a randomly generated event, where the likelihood of each possible reali... An action video game for wagering that determines ...
Folic acid Folic acid may decrease the excretion rate of Colchicine which could result in a higher serum level. Fomepizole Fomepizole may decrease the excretion rate of Colchicine which could result in a higher serum level. Fondaparinux Fondaparinux may decrease the excretion rate of Colchicine which...