Focal adhesion regulation of cell behavior Focal adhesions lie at the convergence of integrin adhesion, signaling and the actin cytoskeleton. Cells modify focal adhesions in response to changes in the molecular composition, two-dimensional (2D) vs. three-dimensional (3D) structur... MA Wozniak - ...
J. Focal adhesion regulation of cell behavior. Biochim Biophys Acta 1692, 103–119, doi: 10.1016/j.bbamcr.2004.04.007 S0167488904000990 (2004). 2. Geiger, B., Bershadsky, A., Pankov, R. & Yamada, K. M. Transmembrane crosstalk between the extracellular matrix–cytoskeleton crosstalk. Nat ...
Wozniak MA, Modzelewska K, Kwong L & Keely PJ (2004). Focal adhesion regulation of cell behavior. Biochim Biophys Acta 1692, 103–119. Wu H, Huang Q, Yuan Y & Granger HJ (1996). VEGF induces NO-dependent hyperpermeability in coronary venules. Am J Physiol 271, H2735–2739. Wu MH...
Directed migration of the transplanted mesenchymal stem cells (MSCs) to the lesion sites plays a pivotal role in the efficacy of cell-based therapy. Our previous study demonstrates that MSCs under varying neural differentiation states possess different m
Adhesive proteins existing in the extracellular matrix (ECM) play important roles in the regulation of neuronal cell behavior, including cell adhesion , motility and neurite outgrowth . Herein we show the effects of a series of adhesive proteins on the neurite outgrowth of PC12 cells and elucidate...
[11]M. A. Wozniak, K. Modzelewska, L. Kwong, and P. J. Keely, “Focal adhesion regulation of cell behavior,” Biochimica et Biophysica Acta, vol. 1692, no. 2-3, pp. 103–119, 2004. [12]R. O. Hynes, “Integrins: versatility, modulation, and signaling in cell adhesion,” Cell...
Focal adhesion regulation of cell behavior. Focal adhesions lie at the convergence of integrin adhesion, signaling and the actin cytoskeleton. Cells modify focal adhesions in response to changes in t... MA Wozniak,K Modzelewska,L Kwong,... - 《Biochimica Et Biophysica Acta Molecular Cell Researc...
For example, EB2 has been demonstrated to play an essential role in the regulation of focal adhesion dynamics and cell migration via its interaction with MAP4K4 [11]. Additionally, our recent work also indicated that EB2 plays a critical role in focal adhesion turnover and epidermal migration...
Here, I focus on some of the general lessons that we have learned from recent studies on cell-ECM adhesion. In addition, I highlight several topics in this rapidly advancing research area. These topics, which include assembly, disassembly and regulation of cell-ECM adhesion structures, the ...
J. Focal adhesion regulation of cell behavior. Biochim. Biophys. Acta 1692, 103–119 (2004). 3. Fenner, J. et al. Macroscopic stiffness of breast tumors predicts metastasis. Sci. Rep. 4, 5512 (2014). 4. Mouw, J. K. et al. Tissue mechanics modulate microRNA-dependent PTEN expression...