Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP. by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry. ...
or an aerosol of FMLP is not due to neutrophil activation; (d) inhalation of FMLP induces BC accompanied by accumulation of activated alveolar macrophages, non-degranulated eosinophils and a few platelet microaggregates in the lung; (e) both cyclo-oxygenase and lipoxygenase metabolites are ...
3.Evaluation of L-selectin expression and assessment of protein tyrosine phosphorylation in bovine polymorphonuclear neutrophil leukocytes around parturition[J].Husheem M;Paape MJ;Wang Y;Capuco AV;Wood L;Monfardini E,Veterinary Research: A Journal on Animal Infection.2002,第3期 4.Flow-...
硕士学位论文 Role of TRPC 1in心压LP.stimulated Neutrophil Direction al Migration Backgrotmd Name:Junchu He Supervisor:Professor Meng Xiaoj ing ABSTRACT Polymorphonuclear leukocytes(PMNs)share of 60%to 70%of the total number of leukocytes in the blood.They are the first-line defense against microor...
We have studied the effect of taxol on two N-formyl-methionyl-leucyl-phenylalanine (FMLP)-induced neutrophil functions and the possible mechanism by which it inhibits these functions. Taxol inhibited FMLP-induced human neutrophil polarization (a characteristic change in neutrophil shape in response to ...
Objectives: To test the hypothesis that simvastatin is capable of blocking human neutrophil degranulation induced by proteinase 3 (PR3)-anti-neutrophil cytoplasm auto-antibodies (ANCA) and myeloperoxidase (MPO)-ANCA, and by the chemotactic and inflammatory peptide N-formyl-methionine-leucine-phenylalanine...
These results show that neutrophil activation involves increased glucose transport and intrinsic activation of glucose transporter molecules. Both tyrosine kinases and PKC are implicated in the activation process. Related ReferencesStaynov, D.Z.; Lee, T.H. 1992: Expression of interleukin-5 and ...
On the basis of the discovery of synergy between chemokines for neutrophil attraction, we extend here this phenomenon between the chemokine MCP-1/CCL2 and the GPCR ligand fMLP or the TLR4 agonist LPS on monocytes. In fact, the bacterial tripeptide fMLP, but not the cytokines IL-1beta or ...
Increased neutrophil receptors for and response to the proinflammatory bacterial peptide formyl-methionyl-leucyl-phenylalanine in Crohn's disease. Neutrophils have an important role in mediating tissue injury in inflammatory bowel disease. The proinflammatory peptide formyl-methionyl-leucyl-phenylalan... PA ...
Inhibition of lymphocyte and neutrophil chemotaxis by pertussis toxin. The cells of the mammalian immune system possess special migratory properties within their in vivo environment, a surveillance characteristic that is thoug... GJ Spangrude,F Sacchi,HR Hill,... - 《Journal of Immunology》...