Although ferroptosis research in many fields is still in its infancy, the number of published papers relating to ferroptosis in aging and degenerative orthopedic diseases has increased exponentially. Therefore, a comprehensive review and in-depth analysis of recent research progress, such as those regard...
Fig. 1: Timeline of ferroptosis research. A brief history of molecular and pharmacological modulators of ferroptosis. Full size image Hallmarks of ferroptosis Morphological features Although an initial study indicated that ferroptosis is morphologically, biochemically and genetically distinct from apoptosis, n...
This paper reviews the pathological mechanism of ferroptosis and DR in recent years and the involvement of ferroptosis in the pathology of DR. In addition, we propose problems that need to be addressed in this research field. It is expected to provide new ideas for treat...
In recent years, modulating ferroptosis to intervene in the occurrence and development of cancer has been a hotspot and focus of etiological research and treatment. Ferroptosis is tightly implicated in tumor biology. On the one hand, tumor suppressors have been found to execute part of their tumor...
2023,Ageing Research Reviews Xv-shenDing, ...BaoWang 2.1Definition of ferroptosis Ferroptosisis a unique form of cell death first proposed in 2012 (Yan et al., 2021). Different from apoptosis, autophagy, necrosis, and pyroptosis, ferroptosis is described as an iron-dependent and regulated form...
ACS Nano. 2023;17(23):23746–60. Article CAS PubMed PubMed Central Google Scholar Zhang Z, Ji Y, Hu N, Yu Q, Zhang X, Li J, et al. Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment. Asian J Pharm Sci. 2022;...
Notably, the most recent research has revealed the intrinsic link between UA and ferroptosis. In this section, we confirm that UA has a large regulatory network and that a single target is not sufficient to exert effective antitumour effects, and thus combination therapy may be a better ...
Find a journal Publish with us Track your research Search Cart Home Scientific Reports Article Identification of ferroptosis and drug resistance related hub genes to predict the prognosis in Hepatocellular CarcinomaArticle Open access Published: 29 May 2023 Volume 13, article number 8681, (2023) ...
In recent years, plenty of reports have suggested that targeting the ferroptosis of renal cells may provide a highly available strategy for treating patients with kidney diseases. In this review, we browse and summarize the current research progress considering the role of ferroptosis in different ...
Iron homeostasis is profoundly impacted by aging. Recent research has revealed that elderly people suffer from cellular iron accumulation, which can result in a variety of tissue degeneration and diseases. Cellular iron deposition caused by aging can occur in various types, such as ferritin, lipofusci...