Recent studies have indicated that ferroptosis plays an essential role in the pathology of neurological diseases, such as intracerebral hemorrhage, ischemic stroke, epilepsy, neurodegenerative diseases, traumatic brain injury and brain cancer. This review focuses on the latest researches on the relationship...
4. Ferroptosis in neurological diseases 5. Discussion and conclusion Ethics approval and consent to participate Consent for publication Availability of data and materials Funding Author contributions Acknowledgments Conflict of interest Abbreviations ReferencesShow full outline Figures (4)Molecular...
Role and mechanism of ferroptosis in neurological diseases. Mol. Metabolism. 61, 101502 (2022). Author contributions Prof. Dr.Sherin Zakaria, Prof. Dr. Walied Abdo, and Prof. Dr.Alaa El-Sisi contributed to conception, design of the study, revising the manuscript and approval of the version ...
Ferroptosis in neurological diseases. Front. Cell. Neurosci. 14, 218 (2020). Article PubMed PubMed Central CAS Google Scholar Mahoney-Sánchez, L. et al. Ferroptosis and its potential role in the physiopathology of Parkinson’s disease. Prog. Neurobiol. 196, 101890 (2021). Article PubMed ...
ferroptosis and reviews the contributions of ferroptosis in neurodegenerative diseases (i.e. Alzheimer’s disease and Parkinson’s disease), traumatic brain injury, as well as hemorrhagic and ischemic stroke, to provide the current understanding of this novel form of cell death in neurological ...
Investigating the specific mechanism of EA for ischemic stroke is anticipated to yield a new scientific basis for targeted therapy of relevant neurological diseases in the future. The etiopathogenesis of ferroptosis is sophisticated and involves multiple transcription factors including p53, NFE2L2, and ...
Emerging mechanisms and targeted therapy of ferroptosis in neurological diseases and neuro-oncology. Int J Biol Sci. 2022;18(10):4260–74. Article CAS PubMed PubMed Central Google Scholar Qi X, Wan Z, Jiang B, Ouyang Y, Feng W, Zhu H, et al. Inducing ferroptosis has the potential to...
Parkinson’s disease. This review summarizes current research on ferroptosis, its underlying mechanisms, and its role in the progression of different neurologic diseases. Understanding the role of ferroptosis could provide valuable information regarding treatment and prevention of these devastating diseases....
diseases through the system Xc−/GSH/GPX4 axis, NAD(P)H/FSP1/CoQ10 axis, iron metabolism pathway and lipid metabolism pathway associated with ferroptosis, as well as its applications in liver disease, neurological diseases, lung injury, heart injury, cancer and other diseases, are summarized ...
Molecular mechanisms of cell death in neurological diseases. Cell Death Differ. 2021;28(7):2029–44. [6] Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, et al. Ferroptosis: A regulated cell death nexus linking metabolism, redox biology, and disease. Cell. 2017...