Here, we provide a brief review for the role of fatty acid metabolism in cancer development with a special focus on fatty acid uptake and de novo synthesis, triglycerides synthesis, storage and degradation. Reprogramming in fatty acid metabolism plays important roles in providing energy, ...
Understanding the mechanism of regulated the fatty acid metabolic pathways in cancer would reveal novel targeted therapy of cancer. 展开 关键词: Fatty acid Synthesis and degradation Enzymes Metabolomics Cancer DOI: 10.1002/ejlt.201600366 年份: 2017 ...
Synthesis and degradationxmlns="http://www.wiley.com/namespaces/wiley" type="main" xml:lang="en"> Fatty acids are fundamental substrates required for energy storage, synthesis of membranes, generation of signaling molecules and lipid droplet formation in cancer cells. High levels of fatty acid ...
Furthermore, the possible role of cannabimimetic fatty acid derivatives in the pathological consequences of cancer and inflammation, such as cachexia, wasting syndrome, chronic pain and local vasodilation, will be examined. 展开 关键词: Anandamides Cannabis sativa Endocannabinoids Hybrid ...
Tumor cells exhibit unique metabolic adaptations that are increasingly viewed as potential targets for novel and specific cancer therapies. Among these targets, the carnitine palmitoyltransferase system is responsible for delivering the long-chain fatty acid (FA) from cytoplasm into mitochondria for oxidatio...
网络脂肪酸的降解 网络释义 1. 脂肪酸的降解 ...质(DNA, RNA, Proteins) 18脂肪酸的降解(Fatty Acid Degradation) 19 脂质(Lipids) 20 凯库勒的苯环结构(Kekulé, Benzene, a… www.docin.com|基于3个网页
英文名称:Fatty Acid Degradation Products 脂肪酸降解产物标准品Fatty Acid Degradation Products Product # Image Description 36357 丙二醛 四丁基*analytical standard 73537 10-十一烯酸analytical standard 61410 反,反-2,4-壬二烯醛analytical standard 90244 ...
Colorectal cancer ELOVL: Elongation of very long-chain fatty acids protein FATP: Fatty acid transport protein FFA: Free fatty acid IS: Internal standard LC: Liquid chromatography MS: Mass spectrometry PC: Phosphatidylcholine PE: Phosphatidylethanolamine ...
Here, we highlight the complexity of cellular fatty acid metabolism in cancer, the various inputs and outputs of the intracellular free fatty acid pool, and the numerous ways that these pathways influence disease behavior.Background Cancer cells have distinctive metabolic phenotypes compared to normal...
The importance of fatty acid (FA) metabolism in cancer is well-established, yet the mechanisms underlying metabolic reprogramming remain elusive. Here, we identify tetraspanin CD37, a prognostic marker for aggressive B-cell lymphoma, as essential membrane-localized inhibitor of FA metabolism. Deletion...