Immunotherapy has become a primary and secondary treatment for gastric cancer (GC) patients with mismatch repair deficiency (dMMR), and is used in both perioperative and advanced stages. The tumor immune microenvironment (TiME) is crucial for immunothera
Immunotherapy has become a primary and secondary treatment for gastric cancer (GC) patients with mismatch repair deficiency (dMMR), and is used in both perioperative and advanced stages. The tumor immune microenvironment (TiME) is crucial for immunothera
成纤维细胞激活蛋白(fibroblast activation protein,FAP)高表达于肿瘤微环境中的肿瘤相关成纤维细胞(cancer associated fibroblasts,CAFs),通过参与细胞外基质(extracellular matrix,ECM)重塑、肿瘤细胞增殖调节和肿瘤免疫抑制等过程促进肿瘤的生长和...
000 deaths annually world-wide. Recently, following its success in previously difficult-to-treat solid tumors, such as melanoma and lung cancer, an immune checkpoint blockade (ICB) strategy was applied to CRC treatment1. There have been many studies exploring T cells...
Cancer-associated fibroblasts are positively correlated with metastatic potential of human gastric cancers J. Exp. Clin. Cancer Res. CR, 29 (2010), p. 66 View in ScopusGoogle Scholar [11] J. Tommelein, L. Verset, T. Boterberg, P. Demetter, M. Bracke, O. De Wever Cancer-associated fi...