Systematic name: Factor Xa (EC 3.4.21.6) Source: Bovine plasma; activated by treatment with the activating enzyme from Russell's viper venom. Concentration: 1 mg/ml (store solution at -20 °C) Storage buffer: Factor Xa protease Ile-Glu/Asp-Gly-Arg is supplied in 20 mM HEPES ...
A mixing test is performed in which the patient's plasma is mixed with normal pooled plasma, incubated at 37°C, and then tested for aPTT. Correction of the aPTT in this test implies a deficiency, whereas persistence of an abnormally prolonged aPTT suggests the presence of an inhibitor. Det...
产品描述 Edoxaban是factor Xa选择性抑制剂,也是具有口服效应的抗凝药物。 信号通路 Metabolism 靶点 Factor Xa Thrombin FIXa - - IC50 0.561nM(Ki) 6μM(Ki) 41.7μM(Ki) - - 体外研究 在人血浆中,0.256和0.508μM的Edoxaban分别加倍凝血酶原时间,并激活部分促凝血酶原激酶时间。 体内研究 在大鼠和...
Lab Test Considerations: Monitor trough FXIII activity levels with each treatment. Potential Nursing DiagnosesIneffective tissue perfusion (Indications) Implementation Dose is based on the most recent trough. If trough level is < 5%,↑ dose by 5 units/kg, if trough level is 5–20% continue with...
体外研究 Apixaban是高度选择且有效作用于,人Factor Xa兔Factor Xa抑制剂,Ki分别为0.08nM和0.17nM。在体外,Apixaban作用于正常人血浆,延长人凝血时间,使凝血酶原时间(PT),改良凝血酶原时间(mPT),活化部分凝血活酶时间(APTT) 和HepTest增加一倍,所需的浓度(EC2x)分别为3.6μM、0.37μM、7.4μM和0.4μM,此外,在...
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Factor Xa was measured by the method of Jobin and Esnouf17 with factor VII– and factor X–deficient plasma. Factors VIII, IX, and XI were measured by a one-stage modified partial thromboplastin time test18 with human factor VIII–, factor IX–, or factor XI–deficient plasma. Assays for...
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The lag time of this system was 40 min in total, largely improves turnaround time compared to conventional in-lab tests. 3.2. Evaluation of the device performance in vitro Real-time anti-factor Xa measurement was achieved by connecting a continuous microfluidic chip to the outlet of a ...
Factor Xa 目录项下的产品 5072-26-4 / MFCD00070309 Buthionine sulfoximine DL-丁硫氨酸-(S,R)-亚砜亚胺 原料0资源0.0询0.0%成交交易量 试剂 √