Pilot study examining anti-factor Xa levels for heparin monitoring and outcomes in patients with cerebral venous thrombosisdoi:10.3389/fmed.2024.1317246Pirahanchi, YasamanSalottolo, KristinBurrell, ChristianXu TangBar-Or, DavidBartt, RussellFrontiers in Medicine...
The feasibility of in vivo real-time monitoring of anti-factor Xa level had been explored using an integrated microdialysis-coupled microfluidic system. By customizing the dialysis membrane and utilizing a fluorogenic substrate, the performance of the integrated device was characterized and tested by con...
Dose adjustment or laboratory monitoring of low-molecular-weight heparin (LMWH) is commonly recommended for patients with severe renal insufficiency (creat... Lim,Wendy - 《Annals of Internal Medicine》 被引量: 973发表: 2006年 Influence of patient characteristics and renal function on factor Xa inh...
The influence of the type of coil (E or K) upon EGF bioactivity, assessed in an in vitro cell assay, was compared to that of the Fc domain of immunoglobulin G by monitoring phosphorylation of EGFR upon chimeric EGF exposure. They demonstrated that the type and the location of the tag ...
Factor Xa represents an attractive target for antithrombotic drugs as blockade of factor Xa permits inhibition of both the extrinsic and intrinsic coagulation pathways. Several factor Xa inhibitors, such as rivaroxaban, apixaban and edoxaban, have been a
After incubation for 30 min at ambient temperatures, residual enzyme activity was determined after the addition of 250 µM SpecXa and monitoring the initial steady-state increase in absorbance at 405 nm. The dissociation constants were determined by fitting the obtained values to the ...
Outcomes of Clinical Nurse Specialist Practice in the Implementation of Video Monitoring at an Academic Medical Center Purpose/Objectives: The purpose of this project was to design and implement a program that utilizes video cameras with the goal of monitoring for and preve... Purvis,Suzanne,Kaun,...
Oral agents that do not require blood level monitoring are presently undergoing taut scrutiny for efficacies and potential side effects, and would potentially soon revolutionize coagulation medicine. The first part of this article reviews oral Factor Xa inhibitors, such as rivaroxaban, apixaban, eriba...
In vivo thrombosis model using rabbits 300 ng/mL FXIa, corresponding to a dose of 450 ng/kg FXIa <300 ng/mL Using the Wessler stasis rabbit model for monitoring clot formation, a dose-dependent increase in the thrombus score was observed using Privigen® spiked with 300–600 ng/mL ...
Chromogenic factor VIII assay preferred for monitoring (1-stage factor VIII assay underestimates factor activity by 50%). b Use of a kaolin-based activated partial thromboplastin time (aPPT) reagent for factor IX assay has been shown to underestimate factor IX levels with this CFC. c Use of ...