Anti–Factor Xa Trough Level–Adjusted Enoxaparin and Venous ThromboembolismAra KoMegan Y. HaradaGalinos BarmparasKevin ChungRussell MasonDorothy A. YimNavpreet DhillonDaniel R. MarguliesBruce L. GewertzEric J. Ley
The feasibility of in vivo real-time monitoring of anti-factor Xa level had been explored using an integrated microdialysis-coupled microfluidic system. By customizing the dialysis membrane and utilizing a fluorogenic substrate, the performance of the integrated device was characterized and tested by con...
A newly implemented deep vein thrombosis/pulmonary embolism treatment protocol, in which patients' doses of IV UFH were adjusted based on blood plasma anti-factor Xa level monitoring, was compared with a deep vein thrombosis/pulmonary embolism protocol, in which patie...
The primary outcome of weight-based rate at first therapeutic anti-Xa level was significantly lower in the obese group, and this was consistent for attainment of steady state, as well (14units/kg/hour vs. 16units/kg/hour, p<0.001). Patients in the obese group had significantly more supra...
anti-Xa 0.2-0.7 0.29(0.18-0.37) 0.36(0.25-0.46) Weak: r = 0.190 (p = 0.064) Yes: Mean anti-Xa significantly lower in patients with thromboembolic events Deshpande et al. anti-Xa 0.3-0.7 - - Weak No: No significant association between anti-Xa level, aPTT, ACT, or heparin dose and ...
一、中文名称:Anti-Human F7/Coagulation factor VII Antibody(3A4)(RHC35902), 重组人凝血因子7抗体 二、产品描述 凝血因子VII是一种依赖维生素K的因子,对止血至关重要。这种因子在血液中以酶原形式循环,并通过因子IXa、因子Xa、因子XIIa或凝血酶进行轻微蛋白水解后转化为活性形式。当因子VII被激活时,会产生一个...
myxa compound when used as an anti-malaria agent (Fig. 2B). The degree of connectivity for each of the 10 com- pounds was evaluated using the compound-targeted genes-connected network, with flavonoids and steroids having the greatest level of connectivity (Table 3). In contrast, other...
acids (L-iduronic or D-glucur- onic acid) and N-acetyl-D-glucosamine [3]. Depending on a contained unique pentasaccharide sequence, heparin exerts anticoagulant activity upon binding with antithrombin, in turn to suppress activa- tion of factor Xa and IIa in the coagulation cascade [1, 3]...
Sípová H, Zhang S, Dudley AM, Galas D, Wang K, Homola J. Surface plasmon resonance biosensor for rapid label-free detection of microribonucleic acid at subfemtomole level. Anal Chem. 2010 Dec 15;82(24):10110-5. Skourti-Stathaki K, Proudfoot NJ, Gromak N. Human senataxin resolves ...
If this screening test indicated relevant level of factor-Xa inhibitor, estimated and measured levels closely agreed (Lin's correlation coefficient close to its maximal value: 95% CI, 0.99-0.99). More than 96% of the estimated levels fell into the predefined range of acceptability (ie, 80%-...