Measurement of whole blood factor Xa-activated clotting time during hemodialysis with low-molecular-weight heparin. J Anesth 1998; 12: 130-132Mori M,Yoshitake S,Kitano T. Measurement of whole blood factor X a-activated clotting time during hemodialysis with low-molecular-weight heparin[J].Journal...
Stages of Blood Coagulation The final stage of blood clotting, the conversion of fibrinogen into fibrin, is catalyzed by a protease called thrombin (or factor IIa), which results from activation of the precursor prothrombin (or factor II), by proteolysis, catalyzed by factor Xa. Two ...
These newer agents do not require any routine laboratory monitoring of blood coagulation; however, biological tests have been developed in order to assess the plasma concentration of these drugs in several clinical settings. This article reviews these 4 oral direct factor Xa inhibitors. View article ...
(in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of...
(in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of ...
Safety not established in patients who have received prothrombin complex concentrates, recombinant factor VIIa, or whole blood products within 7 days prior to the bleeding event.Monitor patients for manifestations of arterial and venous thromboembolic events, ischemic events, and cardiac arrest. Initiate ...
Use of Xa factor inhibitor either per se or in combination with an agent against aggregation of blood platelets and pharmaceutical preparations containing ... B Andr,H Jean-Marc,P Maurice,... 被引量: 0发表: 2000年 YM150, An Oral Direct Factor Xa Inhibitor: Combination with Aspirin or Clopi...
and the vehicle, blood was taken from the inferior vena cava of rats, and platelet-poor plasma (PPP) was then obtained by centrifugation at 2,000 g for 10 min at room temperature to test ex vivo PT and aPTT. Data are presented as the mean ± S D of three independent ...
Serine proteases (SP), including furin, trypsin, and TMPRSS2 cleave the SARS-CoV-2 spike (S) protein, enabling the virus to enter cells. Here, we show that factor (F) Xa, an SP involved in blood coagulation, is upregulated in COVID-19 patients. In contrast to other SPs, FXa exerts...
This study evaluated the effect of both a pneumatic tube delivery system and a rapid, higher-speed centrifuge on a chromogenic amidolytic anti-factor Xa heparin activity assay. Paired tubes of blood were obtained from 54 patients for the... TK Rosborough,PA Wolfson - 《Laboratory Medicine》 被...